Computer‐aided porous implant design for cranio‐maxillofacial defect restoration

The porous structure of the implant contributes significantly to prosthetic osseointegration in cranio‐maxillofacial defect repair surgeries. This study establishes a system called EasyImplant that can easily and efficiently design customized cranio‐maxillofacial implant with porous structure. Healthy side of the skull model is used to obtain the initial implant model on defective side by mirroring method. According to the curvature of undamaged surface, the initial model can be adjusted and repaired. Based on the initial implant model, porous implant structure can be generated efficiently using create sample points, distance Field and marching Cube algorithms. Finally, the connection plate is obtained through surface extruding and model merging. With EasyImplant, a complete porous implant model can be designed in a short time. The proposed methods can contribute to shorten the period of facial implant designing and reduce the incidence of surgical infection.

[1]  Jan Egger,et al.  Computer-aided implant design for the restoration of cranial defects , 2017, Scientific Reports.

[2]  Jan Egger,et al.  Automated Computer-aided Design of Cranial Implants Using a Deep Volumetric Convolutional Denoising Autoencoder , 2019, WorldCIST.

[3]  D. Hutmacher,et al.  Bone Tissue Engineering: Cell Motility, Vascularization, Micro-Nano Scaffolding, and Remodeling , 2014, BioMed Research International.

[4]  D. Ackland,et al.  A personalized 3D-printed prosthetic joint replacement for the human temporomandibular joint: From implant design to implantation. , 2017, Journal of the mechanical behavior of biomedical materials.

[5]  T. Jenkyn,et al.  Development and evaluation of a semi-automatic technique for determining the bilateral symmetry plane of the facial skeleton. , 2013, Medical engineering & physics.

[6]  Manohar Bance Optimizing Ossicular Prosthesis Design and Placement. , 2018, Advances in oto-rhino-laryngology.

[7]  Zhen Li,et al.  High-Resolution Shape Completion Using Deep Neural Networks for Global Structure and Local Geometry Inference , 2017, 2017 IEEE International Conference on Computer Vision (ICCV).

[8]  A. Ow,et al.  Mandibular Reconstruction Using a Custom-Made Titanium Prosthesis: A Case Report on the Use of Virtual Surgical Planning and Computer-Aided Design/Computer-Aided Manufacturing , 2016, Craniomaxillofacial trauma & reconstruction.

[9]  Florian Probst,et al.  Planning of skull reconstruction based on a statistical shape model combined with geometric morphometrics , 2017, International Journal of Computer Assisted Radiology and Surgery.

[10]  André Luiz Jardini,et al.  Customised titanium implant fabricated in additive manufacturing for craniomaxillofacial surgery , 2014 .

[11]  J. Egger,et al.  A review on computer-aided design and manufacturing of patient-specific maxillofacial implants , 2020, Expert review of medical devices.

[12]  Jiawei Feng,et al.  Porous scaffold design by solid T-splines and triply periodic minimal surfaces , 2018, Computer Methods in Applied Mechanics and Engineering.

[13]  S. Hutchins,et al.  Design and fabrication of a finger prosthesis based on a new method of suspension , 2013, Prosthetics and orthotics international.

[14]  D. Yoo Porous scaffold design using the distance field and triply periodic minimal surface models. , 2011, Biomaterials.

[15]  T. Wright,et al.  Reverse Shoulder Arthroplasty Prosthesis Design Classification System. , 2015, Bulletin of the Hospital for Joint Disease.

[16]  D. Yoo New paradigms in hierarchical porous scaffold design for tissue engineering. , 2013, Materials science & engineering. C, Materials for biological applications.

[17]  S. Deogade,et al.  Fabrication of a Cranial Prosthesis Combined with an Ocular Prosthesis Using Rapid Prototyping: A Case Report , 2016, Journal of dentistry.

[18]  Yi Sun,et al.  Development of a computer-aided design software for dental splint in orthognathic surgery , 2016, Scientific reports.

[19]  Christina Gsaxner,et al.  A review on multiplatform evaluations of semi-automatic open-source based image segmentation for cranio-maxillofacial surgery , 2019, Comput. Methods Programs Biomed..

[20]  Wei Xu,et al.  Topological design and additive manufacturing of porous metals for bone scaffolds and orthopaedic implants: A review. , 2016, Biomaterials.

[21]  H. Yoshikawa,et al.  Osteochondral tissue engineering with biphasic scaffold: current strategies and techniques. , 2014, Tissue engineering. Part B, Reviews.

[22]  M. Larosa,et al.  Cranial reconstruction: 3D biomodel and custom-built implant created using additive manufacturing. , 2014, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[23]  A. Vissink,et al.  Digital planning of cranial implants. , 2013, The British journal of oral & maxillofacial surgery.

[24]  Yan Hu,et al.  Osteogenesis of 3D printed porous Ti6Al4V implants with different pore sizes. , 2018, Journal of the mechanical behavior of biomedical materials.

[25]  J. Chaudhuri,et al.  The effect of porosity of a biphasic ceramic scaffold on human skeletal stem cell growth and differentiation in vivo. , 2013, Journal of biomedical materials research. Part A.

[26]  Kuntao Zhou,et al.  Effective method for multi-scale gradient porous scaffold design and fabrication. , 2014, Materials science & engineering. C, Materials for biological applications.