Genomic analysis of benign prostatic hyperplasia implicates cellular re-landscaping in disease pathogenesis.
暂无分享,去创建一个
R. Tibshirani | R. West | J. Brooks | J. Pollack | R. Nolley | Shirley X. Zhu | S. Varma | K. Tu | J. W. Foley | Robert T. Sweeney | Chunfang Zhu | O. Eminaga | Xue Gong | A. S. Pollack | Lance W Middleton | Zhewei Shen | Sujay Vennam | Jewison Biscocho | S. Vennam | Okyaz Eminaga
[1] R. Dhir,et al. Symptomatic and asymptomatic benign prostatic hyperplasia: Molecular differentiation by using microarrays , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[2] R. Mayer,et al. Testosterone and 17β-estradiol induce glandular prostatic growth, bladder outlet obstruction, and voiding dysfunction in male mice. , 2012, Endocrinology.
[3] C. Roehrborn,et al. Lower urinary tract symptoms revisited: a broader clinical perspective. , 2008, European urology.
[4] J. Zhang,et al. Proliferation and differentiation of prostatic stromal cells , 2001, BJU international.
[5] E. Noel,et al. Differential gene expression in the peripheral zone compared to the transition zone of the human prostate gland , 2008, Prostate Cancer and Prostatic Diseases.
[6] R. Dahiya,et al. Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1 , 2007, In Vitro Cellular & Developmental Biology - Animal.
[7] P. Walsh,et al. The development of human benign prostatic hyperplasia with age. , 1984, The Journal of urology.
[8] P. Walsh,et al. The induction of prostatic hypertrophy in the dog with androstanediol. , 1976, The Journal of clinical investigation.
[9] W. Christens-Barry,et al. Prostatic growth rate determined from MRI data: age-related longitudinal changes. , 1999, Journal of andrology.
[10] D. Williams,et al. A human prostatic stromal myofibroblast cell line WPMY-1: a model for stromal-epithelial interactions in prostatic neoplasia. , 1999, Carcinogenesis.
[11] D. Bostwick,et al. The relationship between prostate inflammation and lower urinary tract symptoms: examination of baseline data from the REDUCE trial. , 2008, European urology.
[12] R. West,et al. Gene expression profiling of single cells from archival tissue with laser-capture microdissection and Smart-3SEQ , 2017, Genome Research.
[13] R. Shah,et al. CXCL12 overexpression and secretion by aging fibroblasts enhance human prostate epithelial proliferation in vitro , 2005, Aging cell.
[14] M. Sogayar,et al. Bone Morphogenetic Proteins: structure, biological function and therapeutic applications. , 2014, Archives of biochemistry and biophysics.
[15] T. Mueller,et al. Structural insights into BMP receptors: Specificity, activation and inhibition. , 2016, Cytokine & growth factor reviews.
[16] Christopher A. Miller,et al. VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing. , 2012, Genome research.
[17] David R. Kelley,et al. Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks , 2012, Nature Protocols.
[18] T. Hubbard,et al. A census of human cancer genes , 2004, Nature Reviews Cancer.
[19] M. Barry,et al. THE AMERICAN UROLOGICAL ASSOCIATION SYMPTOM INDEX FOR BENIGN PROSTATIC HYPERPLASIA , 1992, The Journal of urology.
[20] W. Butler,et al. Dentin sialophosphoprotein in biomineralization , 2010, Connective tissue research.
[21] Gabor T. Marth,et al. Haplotype-based variant detection from short-read sequencing , 2012, 1207.3907.
[22] P. di Sant'Agnese,et al. Relationship of neuroendocrine cells of prostate and serotonin to benign prostatic hyperplasia. , 1993, Urology.
[23] K. Miyazono,et al. BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk. , 2005, Cytokine & growth factor reviews.
[24] Serotonin regulates prostate growth through androgen receptor modulation , 2017, Scientific Reports.
[25] Ohad Parnes,et al. Inflammation , 2008, The Lancet.
[26] Arthur P. Grollman,et al. Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing , 2016, Proceedings of the National Academy of Sciences.
[27] J. Macoska,et al. Prostatic fibrosis, lower urinary tract symptoms, and BPH , 2013, Nature Reviews Urology.
[28] E. Giovannucci,et al. Association between markers of the metabolic syndrome and lower urinary tract symptoms in the Third National Health and Nutrition Examination Survey (NHANES III) , 2005, International Journal of Obesity.
[29] W. Mcdougal,et al. Androgen responsiveness of stromal cells of the human prostate: regulation of cell proliferation and keratinocyte growth factor by androgen. , 1998, The Journal of urology.
[30] M. Oberholzer,et al. Light microscopic stereological analysis of the normal human prostate and of benign prostatic hyperplasia. , 1979, The Journal of urology.
[31] P. di Sant'Agnese,et al. Neuroendocrine cells in the human prostate gland. , 1993, Journal of andrology.
[32] H. Hakonarson,et al. ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data , 2010, Nucleic acids research.
[33] M. Carini,et al. Fat boosts, while androgen receptor activation counteracts, BPH‐associated prostate inflammation , 2013, The Prostate.
[34] S. Simon,et al. The genomic landscape of fibrolamellar hepatocellular carcinoma: whole genome sequencing of ten patients , 2015, Oncotarget.
[35] C. Roehrborn,et al. The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia. , 2003, The New England journal of medicine.
[36] Biaoyang Lin,et al. The program of androgen-responsive genes in neoplastic prostate epithelium , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[37] W. Huber,et al. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.
[38] J. McNeal. Origin and evolution of benign prostatic enlargement. , 1978, Investigative urology.
[39] S Miyano,et al. Open source clustering software. , 2004, Bioinformatics.
[40] O. Hofmann,et al. VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research , 2016, Nucleic acids research.
[41] J. Gustafsson,et al. A role for epithelial-mesenchymal transition in the etiology of benign prostatic hyperplasia , 2009, Proceedings of the National Academy of Sciences.
[42] G. Joyce,et al. Economic costs of benign prostatic hyperplasia in the private sector. , 2005, The Journal of urology.
[43] S. J. Higgins,et al. The endocrinology and developmental biology of the prostate. , 1987, Endocrine reviews.
[44] Steven A. Roberts,et al. Mutational heterogeneity in cancer and the search for new cancer-associated genes , 2013 .
[45] G. Bartsch,et al. Human benign prostatic hyperplasia: a stromal disease? New perspectives by quantitative morphology. , 1980, Urology.
[46] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[47] J. Macoska,et al. The inflammatory microenvironment of the aging prostate facilitates cellular proliferation and hypertrophy. , 2008, Cytokine.
[48] D. Peehl,et al. Molecular and cellular pathogenesis of benign prostatic hyperplasia. , 2004, The Journal of urology.
[49] Rohit Mehra,et al. CXC-Type Chemokines Promote Myofibroblast Phenoconversion and Prostatic Fibrosis , 2012, PloS one.
[50] John Trinick,et al. Titin: properties and family relationships , 2003, Nature Reviews Molecular Cell Biology.
[51] C. Roehrborn,et al. 1277: The Impact of Acute or Chronic Inflammation in Baseline Biopsy on the Risk of Clinical Progression of BPH: Results from the MTOPS Study , 2005 .
[52] C. Roehrborn. Prostate size: does it matter? , 2000, Reviews in urology.
[53] R. Tibshirani. Regression Shrinkage and Selection via the Lasso , 1996 .
[54] Richard Durbin,et al. Sequence analysis Fast and accurate short read alignment with Burrows – Wheeler transform , 2009 .
[55] G. Kramer,et al. Phenotypic characterization of infiltrating leukocytes in benign prostatic hyperplasia. , 1992, Laboratory investigation; a journal of technical methods and pathology.
[56] R C Bruskewitz,et al. The effect of finasteride in men with benign prostatic hyperplasia. The Finasteride Study Group. , 2002, The New England journal of medicine.
[57] J. Cyster,et al. CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity. , 2002, Immunity.
[58] H. Klocker,et al. Increased growth factor production in a human prostatic stromal cell culture model caused by hypoxia , 2003, The Prostate.
[59] Alok J. Saldanha,et al. Java Treeview - extensible visualization of microarray data , 2004, Bioinform..
[60] M. Webber,et al. Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18. , 1997, Carcinogenesis.
[61] Andrew E. Jaffe,et al. Bioinformatics Applications Note Gene Expression the Sva Package for Removing Batch Effects and Other Unwanted Variation in High-throughput Experiments , 2022 .
[62] S. Monti,et al. Prevalent decrease of the EGF content in the periurethral zone of BPH tissue induced by treatment with finasteride or flutamide. , 1997, Journal of andrology.
[63] J. Trent,et al. Gene expression signature of benign prostatic hyperplasia revealed by cDNA microarray analysis , 2002, The Prostate.
[64] H. Ahn,et al. Stromal cells of the human prostate: Initial isolation and characterization , 1996, The Prostate.
[65] K. McFann,et al. DHT and testosterone, but not DHEA or E2, differentially modulate IGF-I, IGFBP-2, and IGFBP-3 in human prostatic stromal cells. , 2006, American journal of physiology. Endocrinology and metabolism.
[66] A. Sivachenko,et al. Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples , 2013, Nature Biotechnology.
[67] Steven A. Roberts,et al. Mutational heterogeneity in cancer and the search for new cancer genes , 2014 .
[68] G. Andriole,et al. The effect of finasteride in men with benign prostatic hyperplasia. , 1992, The Journal of urology.
[69] M. Carini,et al. Metabolic syndrome and benign prostatic enlargement: a systematic review and meta‐analysis , 2015, BJU international.
[70] N. Masumori,et al. Distribution of Neuroendocrine Cells in the Transition Zone of the Prostate , 2017, Advances in urology.
[71] F. Watzinger,et al. Bone morphogenetic proteins 5 and 6 stimulate osteoclast generation , 2006 .
[72] Satoru Miyano,et al. Open source clustering software , 2004 .