Chemical Space Mimicry for Drug Discovery
暂无分享,去创建一个
Robert Tibshirani | Albert C. Koong | Quynh-Thu Le | Purvesh Khatri | Peter Lu | Brandon Turner | William Yuan | Dadi Jiang | Dhanya K. Nambiar | Lydia P. Liew | Michael P. Hay | Joshua Bloomstein | Mark G. Moloney | R. Tibshirani | P. Khatri | A. Koong | Q. Le | M. Moloney | M. Hay | William Yuan | Peter Lu | Dhanya K. Nambiar | D. Jiang | L. Liew | J. Bloomstein | Brandon Turner
[1] A. Koong,et al. Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma. , 2011, Blood.
[2] Wolfgang H. B. Sauer,et al. Molecular Shape Diversity of Combinatorial Libraries: A Prerequisite for Broad Bioactivity , 2003, J. Chem. Inf. Comput. Sci..
[3] Dadi Jiang,et al. Targeting the IRE1α-XBP1 branch of the unfolded protein response in human diseases. , 2015, Seminars in cancer biology.
[4] P. Wipf,et al. Stochastic voyages into uncharted chemical space produce a representative library of all possible drug-like compounds. , 2013, Journal of the American Chemical Society.
[5] Xin Wen,et al. BindingDB: a web-accessible database of experimentally determined protein–ligand binding affinities , 2006, Nucleic Acids Res..
[6] Radislav Sedlacek,et al. Catalytic activity of matrix metalloproteinase‐19 is essential for tumor suppressor and anti‐angiogenic activities in nasopharyngeal carcinoma , 2011, International journal of cancer.
[7] Chris Morley,et al. Open Babel: An open chemical toolbox , 2011, J. Cheminformatics.
[8] David N. Beratan,et al. Strategy To Discover Diverse Optimal Molecules in the Small Molecule Universe , 2015, J. Chem. Inf. Model..
[9] CHUN WEI YAP,et al. PaDEL‐descriptor: An open source software to calculate molecular descriptors and fingerprints , 2011, J. Comput. Chem..
[10] Zhiwei Wang,et al. Inhibition of angiogenesis and invasion by 3,3'-diindolylmethane is mediated by the nuclear factor-kappaB downstream target genes MMP-9 and uPA that regulated bioavailability of vascular endothelial growth factor in prostate cancer. , 2007, Cancer research.
[11] Martin Serrano,et al. Nucleic Acids Research Advance Access published October 18, 2007 ChemBank: a small-molecule screening and , 2007 .