J. Garthwaite

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Models of the diffusional spread of nitric oxide: Implications for neural nitric oxide signalling and its pharmacological properties

J. Wood, J. Garthwaite, 1994, Neuropharmacology.

Concepts of neural nitric oxide-mediated transmission

J. Garthwaite, 2008, The European journal of neuroscience.

Glutamate, nitric oxide and cell-cell signalling in the nervous system

J. Garthwaite, 1991, Trends in Neurosciences.

Synaptic activation of metabotropic glutamate receptors in the parallel Fibre-Purkinje cell pathway in rat cerebellar slices

J. Garthwaite, A. Batchelor, D. Madge, 1994, Neuroscience.

Actions of a metabotropic glutamate receptor agonist in immature and adult rat cerebellum.

J. Garthwaite, S. East, 1992, European journal of pharmacology.

Intercellular action of nitric oxide in adult rat cerebellar slices.

J. Garthwaite, E. Southam, 1991, Neuroreport.

Sources and targets of nitric oxide in rat cerebellum

J. Garthwaite, E. Southam, R. Morris, 1992, Neuroscience Letters.

A Kainate Receptor Linked to Nitric Oxide Synthesis from Arginine

J. Garthwaite, E. Southam, M. Anderton, 1989, Journal of neurochemistry.

The nitric oxide-cyclic GMP signalling pathway in rat brain

J. Garthwaite, E. Southam, 1993, Neuropharmacology.

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

J. Garthwaite, S. Charles, R. Chess-Williams, 1988, Nature.

Climbing Fibres as a Source of Nitric Oxide in the Cerebellum

J. Garthwaite, E. Southam, 1991, The European journal of neuroscience.

Comparative effects of some nitric oxide donors on cyclic GMP levels in rat cerebellar slices

J. Garthwaite, E. Southam, 1991, Neuroscience Letters.

Delayed increase of extracellular arginine, the nitric oxide precursor, following electrical white matter stimulation in rat cerebellar slices

C. Hansel, J. Garthwaite, M. Cuénod, 1992, Neuroscience Letters.

NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices.

J. Garthwaite, S. Moncada, R. Palmer, 1989, European journal of pharmacology.

Excitatory Amino Acid Receptors Coupled to the Nitric Oxide/Cyclic GMP Pathway in Rat Cerebellum During Development

J. Garthwaite, S. East, E. Southam, 1991, Journal of neurochemistry.

Glutamate as the Principal Mossy Fibre Transmitter in Rat Cerebellum: pharmacological evidence

J. Garthwaite, A. Brodbelt, 1990, The European journal of neuroscience.

Cellular Origins of Cyclic GMP Responses to Excitatory Amino Acid Receptor Agonists in Rat Cerebellum In Vitro

J. Garthwaite, G. Garthwaite, 1987, Journal of neurochemistry.

Guanylate cyclase activities in enriched preparations of neurones, astroglia and a synaptic complex isolated from rat cerebellum

J. Garthwaite, G. Wilkin, S. Bunn, 1986, Neurochemistry International.

Nitric oxide-dependent long-term potentiation is blocked by a specific inhibitor of soluble guanylyl cyclase

J. Garthwaite, E. Southam, C. Boulton, 1995, Neuroscience.

Nanomolar N(G)-nitroarginine inhibits NMDA-induced cyclic GMP formation in rat cerebellum.

J. Garthwaite, S. East, 1990, European journal of pharmacology.

Trans‐ACPD-induced Ca2+ signals in cerebellar Purkinje cells

B. Gähwiler, J. Garthwaite, T. Knöpfel, 1991, Neuroreport.

The gentle art of saying NO: how nitric oxide gets things done in the hypothalamus

J. Garthwaite, V. Prévot, Konstantina Chachlaki, 2017, Nature Reviews Endocrinology.

Inactivation of nitric oxide by rat cerebellar slices

J. Garthwaite, C. Hall, 2006, The Journal of physiology.

Exquisite sensitivity to subsecond, picomolar nitric oxide transients conferred on cells by guanylyl cyclase-coupled receptors

Kara F. Held, J. Garthwaite, A. Batchelor, 2010, Proceedings of the National Academy of Sciences.

From synaptically localized to volume transmission by nitric oxide

J. Garthwaite, 2016, The Journal of physiology.

On the Role of Nitric Oxide in Hippocampal Long-Term Potentiation

John Garthwaite, J. Garthwaite, C. Bon, 2003, The Journal of Neuroscience.

Frequency detection and temporally dispersed synaptic signal association through a metabotropic glutamate receptor pathway

John Garthwaite, J. Garthwaite, A. Batchelor, 1997, Nature.

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors

Stephen P. H. Alexander, C. Southan, D. Fabbro, 2021, British journal of pharmacology.

mGlu1 receptors mediate a post‐tetanic depression at parallel fibre–Purkinje cell synapses in rat cerebellum

J. Garthwaite, A. Batchelor, A. Batchelor, 2001, The European journal of neuroscience.

What is the real physiological NO concentration in vivo?

John Garthwaite, J. Garthwaite, C. Hall, 2009, Nitric oxide : biology and chemistry.

Nitric oxide signaling in the central nervous system.

J Garthwaite, J. Garthwaite, C. Boulton, 1995, Annual review of physiology.

N10‐carbonyl‐substituted phenothiazines inhibiting lipid peroxidation and associated nitric oxide consumption powerfully protect brain tissue against oxidative stress

J. Garthwaite, D. Selwood, T. Bellamy, 2019, Chemical biology & drug design.

NITRIC-OXIDE SIGNALING IN THE NERVOUS-SYSTEM

J. Garthwaite, 1993 .

Quinolinate mimics neurotoxic actions of N-methyl-d-aspartate in rat cerebellar slices

J. Garthwaite, G. Garthwaite, 1987, Neuroscience Letters.

A new and simple method for delivering clamped nitric oxide concentrations in the physiological range: application to activation of guanylyl cyclase-coupled nitric oxide receptors.

J. Garthwaite, T. Bellamy, Victoria Wykes, 2003, Molecular pharmacology.

Amino acid neurotoxicity: Intracellular sites of calcium accumulation associated with the onset of irreversible damage to rat cerebellar neurones in vitro

J. Garthwaite, G. Garthwaite, 1986, Neuroscience Letters.

NOS1 mutations cause hypogonadotropic hypogonadism with sensory and cognitive deficits that can be reversed in infantile mice

A. Carleton, J. Garthwaite, P. Avan, 2022, Science Translational Medicine.

The shaping of nitric oxide signals by a cellular sink

J. Garthwaite, C. Griffiths, 2001, The Journal of physiology.

Imidazol-1-ylethylindazole Voltage-Gated Sodium Channel Ligands Are Neuroprotective during Optic Neuritis in a Mouse Model of Multiple Sclerosis

J. Garthwaite, K. Lidster, D. Selwood, 2014, Journal of medicinal chemistry.

State-dependent inhibition of Na+ currents by the neuroprotective agent 619C89 in rat hippocampal neurons and in a mammalian cell line expressing rat brain type IIA Na+ channels

J. Garthwaite, X. Xie, X. Xie, 1996, Neuroscience.

Receptor guanylyl cyclase (RGC) family in GtoPdb v.2021.3

J. Garthwaite, S. Waldman, J. Stasch, 2021, IUPHAR/BPS Guide to Pharmacology CITE.

Receptor guanylyl cyclase (RGC) family (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

J. Garthwaite, S. Waldman, J. Stasch, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Sub-second Kinetics of the Nitric Oxide Receptor, Soluble Guanylyl Cyclase, in Intact Cerebellar Cells*

Tomas C. Bellamy, J. Garthwaite, T. Bellamy, 2001, The Journal of Biological Chemistry.

The synaptic potential mediated by metabotropic glutamate receptors is not associated with a substantial elevation of cytosolic free calcium concentration in purkinje cells

J. Garthwaite, I. Vranesic, T. Knoepfel, 1996, Neuropharmacology.

Ludimus Innocui: Interpreting Martial’S Imperial Epigrams

J. Garthwaite, 2009 .

The Panegyrics of Domitian in Martial Book 9

J. Garthwaite, 1993, Ramus.

Writing Politics in Imperial Rome

J. Garthwaite, W. J. Dominik, P. Roche, 2009 .

Statius’ Retirement from Rome: Silvae 3.5

J. Garthwaite, 1989, Antichthon.

Martial, Book 6, on Domitian's Moral Censorship

J. Garthwaite, 1990 .

Selective loss of Purkinje and granule cell responsiveness to N-methyl-D-aspartate in rat cerebellum during development.

J. Garthwaite, G. Garthwaite, B. Yamini, 1987, Brain research.

Excitatory amino acid neurotoxicity and neurodegenerative disease.

J. Garthwaite, B. Meldrum, 1990, Trends in pharmacological sciences.

Nitric Oxide Is Required for L-Type Ca2+ Channel-Dependent Long-Term Potentiation in the Hippocampus

J. Garthwaite, B. Pigott, 2016, Front. Synaptic Neurosci..

"cAMP-specific" phosphodiesterase contributes to cGMP degradation in cerebellar cells exposed to nitric oxide.

Tomas C. Bellamy, J. Garthwaite, T. Bellamy, 2001, Molecular pharmacology.

Dual-component NMDA receptor currents at a single central synapse

E. D'Angelo, E. D’Angelo, J. Garthwaite, 1990, Nature.

Oxadiazolylindazole sodium channel modulators are neuroprotective toward hippocampal neurones.

J. Garthwaite, B. Lancaster, P. Gane, 2009, Journal of medicinal chemistry.

Mechanisms of AMPA Neurotoxicity in Rat Brain Slices

J. Garthwaite, G. Garthwaite, 1991, The European journal of neuroscience.

Excitatory Amino Acid Neurotoxicity in Rat Brain Slices

J. Garthwaite, G. Garthwaite, G. D. Williams, 1991 .

Tyrosine Kinase Is Required for Long-Term Depression in the Cerebellum

J. Garthwaite, B. Lancaster, A. R. Boxall, 1996, Neuron.

Signaling from Blood Vessels to CNS Axons through Nitric Oxide

Katalin Bartus, John Garthwaite, David Goodwin, 2006, The Journal of Neuroscience.

NMDA receptor activation in rat hippocampus induces cyclic GMP formation through the l-arginine-nitric oxide pathway

J. Garthwaite, S. East, 1991, Neuroscience Letters.

Pharmacological antagonism of the actions of group II and III mGluR agonists in the lateral perforant path of rat hippocampal slices

G. Collingridge, H. Tse, D. Jane, 1996, British journal of pharmacology.

Adenosine acting on A1 receptors protects NO-triggered rebound potentiation and LTP in rat hippocampal slices.

J. Garthwaite, C. Bon, 2002, Journal of neurophysiology.

Adenosine Acting on A 1 Receptors Protects NO-Triggered Rebound Potentiation and LTP in Rat Hippocampal Slices

J. Garthwaite, C. Bon, 2002 .

Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one.

J. Garthwaite, E. Southam, B. Mayer, 1995, Molecular pharmacology.

Sites ofd-[3H]aspartate accumulation in mouse cerebellar slices

J. Garthwaite, G. Garthwaite, 1985, Brain Research.

Putative acidic amino acid transmitters in the cerebellum. II. Electron microscopic localization of transport sites

J. Garthwaite, G. Wilkin, R. Bala´zs, 1982, Brain Research.

Toxic effects of α-aminoadipate on cultured cerebellar cells

J. Garthwaite, C. Regan, 1980, Brain Research.

Tonic and Phasic Nitric Oxide Signals in Hippocampal Long-Term Potentiation

J. Garthwaite, R. Hopper, 2006, The Journal of Neuroscience.

Exogenous nitric oxide causes potentiation of hippocampal synaptic transmission during low‐frequency stimulation via the endogenous nitric oxide–cGMP pathway

J. Garthwaite, C. Bon, 2001, The European journal of neuroscience.

Nitric oxide-induced potentiation of CA1 hippocampal synaptic transmission during baseline stimulation is strictly frequency-dependent

J. Garthwaite, C. Bon, 2001, Neuropharmacology.

The Nitric Oxide ‐ Cyclic GMP Pathway and Synaptic Depression in Rat Hippocampal Slices

G. Collingridge, J. Garthwaite, A. Irving, 1994, The European journal of neuroscience.

Regulation of synaptic transmission in the mossy fibre-granule cell pathway of rat cerebellum by metabotropic glutamate receptors

J. Garthwaite, A. Batchelor, P. Vetter, 1999, Neuropharmacology.

Novel synaptic potentials in cerebellar Purkenje cells: Probable mediation by metabotropic glutamate receptors

J. Garthwaite, A. Batchelor, 1993, Neuropharmacology.

Morphological response of endoplasmic reticulum in cerebellar Purkinje cells to calcium deprivation

J. Garthwaite, G. Garthwaite, F. Hajós, 1992, Neuroscience.

A Novel Drug Binding Site on Voltage-Gated Sodium Channels in Rat Brain

John Garthwaite, J. Garthwaite, M. Leach, 2006, Molecular Pharmacology.

Cyclic GMP and cell death in rat cerebellar slices

J. Garthwaite, G. Garthwaite, 1988, Neuroscience.

Ex Vivo Measurement of Brain Tissue Nitrite and Nitrate Accurately Reflects Nitric Oxide Synthase Activity In Vivo

J. Garthwaite, M. Salter, P. Strijbos, 1996, Journal of neurochemistry.

Nitric oxide signalling in the nervous system

J. Garthwaite, 1993 .

Kainic acid receptors and neurotoxicity in adult and immature rat cerebellar slices

J. Garthwaite, G. Wilkin, 1982, Neuroscience.

Cellular uptake disguises action of L‐glutamate on N‐methyl‐D‐aspartate receptors: With an appendix: Diffusion of transported amino acids into brain slices

J. Garthwaite, 1985, British journal of pharmacology.

Long‐Term Depression in Rat Cerebellum Requires both NO Synthase and NO‐sensitive Guanylyl Cyclase

J. Garthwaite, A. R. Boxall, Andrew R. Boxall, 1996, The European journal of neuroscience.

Isolation and Biochemical Characterization of Morphologically Defined Structures, Including Cell Types, from the Cerebellum

R. Balázs, J. Garthwaite, P. Woodhams, 1978 .

With anappendix: Diffusion oftransported aminoacids into brain slices

J. Garthwaite, 1985 .

MUSCARINIC RECEPTORS IN RAT SYMPATHETIC GANGLIA

J. Garthwaite, D. Brown, R. D. White, 1980, British journal of pharmacology.

Glutamate Toxicity: An Experimental and Theoretical Analysis

J. Garthwaite, G. Garthwaite, G. D. Williams, 1992, The European journal of neuroscience.

Leptin-dependent neuronal NO signaling in the preoptic hypothalamus facilitates reproduction.

J. Garthwaite, S. Bouret, W. Colledge, 2014, The Journal of clinical investigation.

Lesional-targeting of neuroprotection to the inflammatory penumbra in experimental multiple sclerosis.

J. Garthwaite, S. Joel, G. Giovannoni, 2014, Brain : a journal of neurology.

The Physiological Roles of Nitric Oxide in the Central Nervous System

J. Garthwaite, 2000 .

The nitric oxide-cyclic GMP pathway is required for nociceptive signalling at specific loci within the somatosensory pathway

J. Garthwaite, M. Salter, S. Neale, 1996, Neuroscience.

Soluble guanylyl cyclase activator YC-1 protects white matter axons from nitric oxide toxicity and metabolic stress, probably through Na(+) channel inhibition.

J. Garthwaite, G. Garthwaite, D. Goodwin, 2002, Molecular pharmacology.

ACTION OF SURUGATOXIN ON NICOTINIC RECEPTORS IN THE SUPERIOR CERVICAL GANGLION OF THE RAT

J. Garthwaite, S. Yamada, D. Brown, 1976, British journal of pharmacology.

Kinetics of a Cellular Nitric Oxide/cGMP/Phosphodiesterase-5 Pathway*

I. H. Bianco, J. Garthwaite, E. Mo, 2004, Journal of Biological Chemistry.

Receptor-linked ionic channels mediate N-methyl-d-aspartate neurotoxicity in rat cerebellar slices

J. Garthwaite, G. Garthwaite, 1987, Neuroscience Letters.

Ionic requirements for neurotoxic effects of excitatory amino acid analogues in rat cerebellar slices

J. Garthwaite, G. Garthwaite, F. Hajós, 1986, Neuroscience.

On the selectivity of neuronal NOS inhibitors

J. Garthwaite, K. Bartus, B. Pigott, 2013, British journal of pharmacology.

Superoxide-dependent consumption of nitric oxide in biological media may confound in vitro experiments.

J. Garthwaite, R. Keynes, C. Griffiths, 2003, The Biochemical journal.

Serum S-100 Protein, Relationship to Clinical Outcome in Acute Stroke

J. Garthwaite, R. Sherwood, P. Bath, 1997, Annals of clinical biochemistry.

Nitric oxide activation of guanylyl cyclase in cells revisited

J. Garthwaite, B. Roy, Brijesh Roy, 2006, Proceedings of the National Academy of Sciences.

Properties of NO‐activated guanylyl cyclases expressed in cells

J. Garthwaite, Victoria Wykes, V. Wykes, 2003, British journal of pharmacology.

Pharmacology of the nitric oxide receptor, soluble guanylyl cyclase, in cerebellar cells

J. Garthwaite, T. Bellamy, Tomas C. Bellamy, 2002, British journal of pharmacology.

On the activation of soluble guanylyl cyclase by nitric oxide

Tomas C. Bellamy, J. Wood, J. Garthwaite, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Nitric oxide as a multimodal brain transmitter

J. Garthwaite, 2018, Brain and neuroscience advances.

Separation of Cell Types from the Cerebellum and Their Properties

R. Balázs, J. Garthwaite, 1981 .

Reversible and irreversible neuronal damage caused by excitatory amino acid analogues in rat cerebellar slices

J. Garthwaite, G. Garthwaite, F. Hajós, 1986, Neuroscience.

Neurotoxicity of excitatory amino acid receptor agonists in rat cerebellar slices: Dependence on calcium concentration

J. Garthwaite, G. Garthwaite, 1986, Neuroscience Letters.

Trans-Synaptic Signalling by Nitric Oxide

J. Garthwaite, C. Hall, 2005 .

Substantial regional and hemispheric differences in brain nitric oxide synthase (NOS) inhibition following intracerebroventricular administration of N ω -nitro-l-arginine (L-NA) and its methyl ester (L-NAME)

J. Garthwaite, M. Salter, P. Strijbos, 1995, Neuropharmacology.

NO as a multimodal transmitter in the brain: discovery and current status

J. Garthwaite, 2018, British journal of pharmacology.

Hippocampal neurons in organotypic slice culture are highly resistant to damage by endogenous and exogenous nitric oxide

J. Garthwaite, R. Keynes, S. Duport, 2004, The European journal of neuroscience.

Pathological consequences of inducible nitric oxide synthase expression in hippocampal slice cultures

J. Garthwaite, S. Duport, John Garthwaite, 2005, Neuroscience.

Differential sensitivity of rat cerebellar cells in vitro to the neurotoxic effects of excitatory amino acid analogues

J. Garthwaite, G. Garthwaite, 1984, Neuroscience Letters.

Metabotropic glutamate receptor subtypes modulating neurotransmission at parallel fibre–Purkinje cell synapses in rat cerebellum

J. Garthwaite, A. Batchelor, S. Neale, 2001, Neuropharmacology.

Synaptic excitation mediated by AMPA receptors in rat cerebellar slices is selectively enhanced by aniracetam and cyclothiazide

J. Garthwaite, A. R. Boxall, Andrew R. Boxall, 1995, Neurochemical Research.

A biplanar slice preparation for studying cerebellar synaptic transmission

J. Garthwaite, A. Batchelor, 1996, Journal of Neuroscience Methods.

GABAB Receptors in the Parallel Fibre Pathway of Rat Cerebellum

J. Garthwaite, A. Batchelor, 1992, The European journal of neuroscience.

Synaptic activation of N-methyl-d-aspartate and non-N-methyl-d-aspartate receptors in the mossy fibre pathway in adult and immature rat cerebellar slices

J. Garthwaite, A. Brodbelt, 1989, Neuroscience.

Excitatory amino acid receptors in the parallel fibre pathway in rat cerebellar slices

J. Garthwaite, Peter S. Beaumont, 1989, Neuroscience Letters.

Quisqualate neurotoxicity: A delayed, CNQX-sensitive process triggered by a CNQX-insensitive mechanism in young rat hippocampal slices

J. Garthwaite, G. Garthwaite, 1989, Neuroscience Letters.

Morphological and electrophysiological characteristics of rat cerebellar slices maintained in vitro.

F. Crépel, J. Garthwaite, S. Dhanjal, 1981, The Journal of physiology.

Improved genetically-encoded, FlincG-type fluorescent biosensors for neural cGMP imaging

Katherine C. Wood, J. Garthwaite, C. Allerston, 2013, Front. Mol. Neurosci..

Pharmacological Characterization of Synaptic Transmission through mGluRs in Rat Cerebellar Slices

J. Garthwaite, T. Knöpfel, F. Gasparini, 1997, Neuropharmacology.

Amino acid neurotoxicity: Relationship to neuronal depolarization in rat cerebellar slices

J. Garthwaite, G. Garthwaite, F. Hajós, 1986, Neuroscience.

Rapid desensitization of the nitric oxide receptor, soluble guanylyl cyclase, underlies diversity of cellular cGMP responses.

J Garthwaite, Tomas C. Bellamy, J. Wood, 2000, Proceedings of the National Academy of Sciences of the United States of America.

The receptor-like properties of nitric oxide-activated soluble guanylyl cyclase in intact cells

Tomas C. Bellamy, J. Garthwaite, T. Bellamy, 2004, Molecular and Cellular Biochemistry.

Neuronal nitric oxide synthase and the serotonin transporter get harmonious

J. Garthwaite, 2007, Proceedings of the National Academy of Sciences.

Kinetics of nitric oxide‐cyclic GMP signalling in CNS cells and itspossible regulation by cyclic GMP

Tomas C. Bellamy, J. Garthwaite, T. Bellamy, 2002, Journal of neurochemistry.

Dynamics of cellular NO-cGMP signaling.

J. Garthwaite, 2005, Frontiers in bioscience : a journal and virtual library.

Dynamics of nitric oxide during simulated ischaemia‐reperfusion in rat striatal slices measured using an intrinsic biosensor, soluble guanylyl cyclase

J. Garthwaite, G. Garthwaite, C. Griffiths, 2002, The European journal of neuroscience.

NMDA receptors, neuronal development, and neurodegeneration

J. Garthwaite, 1995 .

Nitric oxide toxicity in CNS white matter: an in vitro study using rat optic nerve

J. Garthwaite, A. Batchelor, G. Garthwaite, 2002, Neuroscience.

N10‐carbonyl‐substituted phenothiazines inhibiting lipid peroxidation and associated nitric oxide consumption powerfully protect brain tissue against oxidative stress

Tomas C. Bellamy, J. Garthwaite, D. Selwood, 2019, Chemical biology & drug design.

On the preparation of brain slices: morphology and cyclic nucleotides

R. Balázs, J. Garthwaite, P. Woodhams, 1979, Brain Research.

The mechanism of kainic acid neurotoxicity

J. Garthwaite, G. Garthwaite, 1983, Nature.

Inhibition of nitric oxide‐activated guanylyl cyclase by calmodulin antagonists

J. Garthwaite, C. Griffiths, LR James, 2009, British journal of pharmacology.

Brill’s Companions in Classical Studies

J. Garthwaite, W. J. Dominik, P. Roche, 2009 .

In vitro neurotoxicity of excitatory acid analogues during cerebellar development

J. Garthwaite, G. Garthwaite, 1986, Neuroscience.

Nitric oxide and its role in ischaemic brain injury.

J. Garthwaite, R. Keynes, Robert G. Keynes, 2004, Current molecular medicine.

Serum S-100 Protein, Relationship to Clinical Outcome in Acute Stroke

J. Garthwaite, R. Sherwood, P. Bath, 1997, Annals of clinical biochemistry.

Serum neuron-specific enolase, carnosinase, and their ratio in acute stroke. An enzymatic test for predicting outcome?

J. Garthwaite, R. Sherwood, P. Bath, 1996, Stroke.

Glutamate Receptors, Nitric Oxide, and Cyclic GMP

J. Garthwaite, E. Southam, S. J. East, 1991 .

Pathological implications of iNOS expression in central white matter: an ex vivo study of optic nerves from rats with experimental allergic encephalomyelitis

J. Garthwaite, M. Cuzner, A. Batchelor, 2005, The European journal of neuroscience.

Subunits of the nitric oxide receptor, soluble guanylyl cyclase, expressed in rat brain

J. Garthwaite, B. Gibb, Barry J. M. Gibb, 2001, The European journal of neuroscience.

Excitatory amino acid receptors and guanosine 3',5'-cyclic monophosphate in incubated slices of immature and adult rat cerebellum

J. Garthwaite, 1982, Neuroscience.

Excitatory amino acid-induced changes in cyclic GMP levels in slices and cell suspensions from the cerebellum.

R. Balázs, J. Garthwaite, 1981, Advances in biochemical psychopharmacology.

Selective blockade of N-methyl-D-aspartate receptor function by the nitric oxide donor, nitroprusside.

J. Garthwaite, A. Batchelor, S. East, 1991, European journal of pharmacology.

Hyperpolarization-activated ion channels as targets for nitric oxide signalling in deep cerebellar nuclei

J. Garthwaite, Gary W Wilson, 2010, The European journal of neuroscience.

Inter-Cellular Signalling by Nitric Oxide

J. Garthwaite, E. Southam, R. Morris, 1993 .

Electron microscopic autoradiography of d-[3H]aspartate uptake sites in mouse cerebellar slices shows poor labelling of mossy fibre terminals

J. Garthwaite, G. Garthwaite, 1988, Brain Research.

A morphological study of incubated slices of rat cerebellum in relation to postnatal age.

R. Balázs, J. Garthwaite, P. Woodhams, 1980, Developmental neuroscience.

Neural nitric oxide signalling

J. Garthwaite, 1995, Trends in Neurosciences.

Nitric oxide does not mediate acute glutamate neurotoxicity, nor is it neuroprotective, in rat brain slices

J. Garthwaite, G. Garthwaite, 1994, Neuropharmacology.

Nitric oxide-cyclic GMP pathway in brain slices.

J. Garthwaite, E. Southam, 1996, Methods in enzymology.

Hippocampal Slices NO-Triggered Rebound Potentiation and LTP in Rat Adenosine Acting on A1 Receptors Protects

P. Husbands, B. Fredholm, J. Garthwaite, 2015 .

Mechanisms of Activity-dependent Plasticity in Cellular Nitric Oxide-cGMP Signaling*

J. Garthwaite, J. Vernon, E. Halvey, 2009, The Journal of Biological Chemistry.

New insight into the functioning of nitric oxide-receptive guanylyl cyclase: physiological and pharmacological implications

J. Garthwaite, 2009, Molecular and Cellular Biochemistry.

Membrane‐association and the sensitivity of guanylyl cyclase‐coupled receptors to nitric oxide

J. Garthwaite, Victoria Wykes, 2004, British journal of pharmacology.

AMPA Neurotoxicity in Rat Cerebellar and Hippocampal Slices: Histological Evidence for Three Mechanisms

J. Garthwaite, G. Garthwaite, 1991, The European journal of neuroscience.

Interaction of the antiepileptic drug lamotrigine with recombinant rat brain type IIA Na+ channels and with native Na+ channels in rat hippocampal neurones

John Garthwaite, J. Garthwaite, B. Lancaster, 1995, Pflügers Archiv.

Differential dependence on Ca2+ of N-methyl-d-aspartate and quisqualate neurotoxicity in young rat hippocampal slices

J. Garthwaite, G. Garthwaite, 1989, Neuroscience Letters.

Differential Sensitivity of Guanylyl Cyclase and Mitochondrial Respiration to Nitric Oxide Measured Using Clamped Concentrations*

John Garthwaite, J. Garthwaite, T. Bellamy, 2002, The Journal of Biological Chemistry.

Nitric oxide may act as a messenger between dorsal root ganglion neurones and their satellite cells

J. Garthwaite, E. Southam, R. Morris, 1992, Neuroscience Letters.

Nitric oxide targets oligodendrocytes and promotes their morphological differentiation

J. Garthwaite, G. Garthwaite, D. Goodwin, 2014, Glia.

Picomolar Nitric Oxide Signals from Central Neurons Recorded Using Ultrasensitive Detector Cells

Katherine C. Wood, J. Garthwaite, A. Batchelor, 2011, The Journal of Biological Chemistry.

An Enzyme-linked Receptor Mechanism for Nitric Oxide-activated Guanylyl Cyclase*

J. Garthwaite, E. Halvey, B. Roy, 2008, Journal of Biological Chemistry.

Probing the presence of the ligand‐binding haem in cellular nitric oxide receptors

J. Garthwaite, J. Vernon, E. Mo, 2008, British journal of pharmacology.

Supersensitivity to the cyclic GMP response to glutamate during cerebellar maturation

R. Balázs, J. Garthwaite, 1978, Nature.

Kainate-glutamate interactions in rat cerebellar slices

J. Garthwaite, G. Gilligan, 1984, Neuroscience.

Antagonism of the synaptic depressant actions of l-AP4 in the lateral perforant path by MAP4

H. Tse, D. Jane, J. Garthwaite, 1995, Neuropharmacology.

A new small molecule inhibitor of soluble guanylate cyclase

J. Garthwaite, C. Allerston, P. Gane, 2015, Bioorganic & medicinal chemistry.

Neurotoxicity of excitatory amino acid receptor agonists in young rat hippocampal slices

J. Garthwaite, G. Garthwaite, 1989, Journal of Neuroscience Methods.

Excitatory amino acid receptors and channels

J. Garthwaite, 1990 .

The NO‐cGMP Pathway in Neonatal Rat Dorsal Horn

J. Garthwaite, E. Southam, R. Morris, 1994, The European journal of neuroscience.

Mechanism of action of lamotrigine

J. Garthwaite, 1996 .

Nitric oxide inactivation in brain by a novel O2-dependent mechanism resulting in the formation of nitrate ions.

J. Garthwaite, B. Yamini, C. Hall, 2002, The Biochemical journal.

Surface plasmon resonance using the catalytic domain of soluble guanylate cyclase allows the detection of enzyme activators☆

J. Garthwaite, C. Allerston, D. Selwood, 2014, Bioorganic & medicinal chemistry letters.

The mechanism of kainic acid neurotoxicity (reply)

J. Garthwaite, G. Garthwaite, 1984, Nature.

Cellular Targets of Nitric Oxide in the Hippocampus

Katalin Bartus, John Garthwaite, J. Garthwaite, 2013, PloS one.

Vicious Cycle Involving Na+ Channels, Glutamate Release, and NMDA Receptors Mediates Delayed Neurodegeneration through Nitric Oxide Formation

J. Garthwaite, M. Leach, P. Strijbos, 1996, The Journal of Neuroscience.

On the regulation of NMDA receptors by nitric oxide

J. Garthwaite, B. Lancaster, R. Hopper, 2004, The European journal of neuroscience.

Mechanisms of excitatory amino acid neurotoxicity in rat brain slices.

J. Garthwaite, G. Garthwaite, 1990, Advances in experimental medicine and biology.

Cytochrome P450 oxidoreductase participates in nitric oxide consumption by rat brain

J. Garthwaite, C. Hall, R. Keynes, 2009, The Biochemical journal.

CGMP MAY MEDIATE TRANSIENT SYNAPTIC DEPRESSION IN RAT HIPPOCAMPAL SLICES

J. Garthwaite, C. Boulton, A. Irving, 1993 .

Excitatory Amino Acids in the Cerebellum: Receptor Types and Receptive Cells

J. Garthwaite, 1982 .

Intracellular pH and the distribution of weak acids and bases in isolated rat superior cervical ganglia.

D. A. Brown, J. Garthwaite, 1979, The Journal of physiology.

Discrepancies in the extracellular space of sympathetic ganglia measured using different isotopes of mannitol and sucrose

J. Garthwaite, 1979, Journal of Neuroscience Methods.

Molecular Characterization and In Situ Localization Of A Full‐Length Cyclic Nucleotide‐Gated Channel In Rat Brain

Ian G. Charles, J. Garthwaite, P. Strijbos, 1999, The European journal of neuroscience.

Nitric oxide stimulates cGMP formation in rat optic nerve axons, providing a specific marker of axon viability

J. Garthwaite, G. Garthwaite, D. A. Goodwin, 1999, The European journal of neuroscience.

The nitric oxide‐cyclic GMP pathway and synaptic plasticity in the rat superior cervical ganglion

J. Garthwaite, E. Southam, S. Charles, 1996, British journal of pharmacology.

NADPH-diaphorase staining in autonomic and somatic cranial ganglia of the rat.

J. Garthwaite, E. Southam, R. Morris, 1993, Neuroreport.

Mechanisms of ischaemic damage to central white matter axons: a quantitative histological analysis using rat optic nerve

D. A. Goodwin, J. Garthwaite, A. Batchelor, 1999, Neuroscience.

Hyperpolarization-activated ion channels as targets for nitric oxide signalling in deep cerebellar nuclei

J. Garthwaite, Gary W Wilson, 2010, The European journal of neuroscience.

Vicious Cycle Involving Na+ Channels, Glutamate Release, and NMDA Receptors Mediates Delayed Neurodegeneration through Nitric Oxide Formation

J. Garthwaite, M. Leach, P. Strijbos, 1996, The Journal of Neuroscience.

Nitric oxide consumption through lipid peroxidation in brain cell suspensions and homogenates.

J. Garthwaite, C. Hall, C. Griffiths, 2005, The Biochemical journal.

Lesional-targeting of neuroprotection to the inflammatory penumbra in experimental multiple sclerosis.

J. Garthwaite, S. Joel, G. Giovannoni, 2014, Brain : a journal of neurology.

Dynamics of a NO-cGMP phosphorylation pathway

J. Garthwaite, E. Mo, Hemisha Amin, 2003 .

Exquisite sensitivity to subsecond, picomolar nitric oxide transients conferred on cells by guanylyl cyclase-coupled receptors

Kara F. Held, J. Garthwaite, A. Batchelor, 2010, Proceedings of the National Academy of Sciences.

Leptin-dependent neuronal NO signaling in the preoptic hypothalamus facilitates reproduction.

J. Garthwaite, S. Bouret, W. Colledge, 2014, The Journal of clinical investigation.