Image Guided Microscopic Surgery System Using Mutual-Information Based Registraion

We have developed an image guided microscopic surgery system for the navigation of surgical procedures that can overlay renderings of anatomical structures that are otherwise invisible. A new histogram-based mutual information maximization technique was applied for alignment of the scope view and three-dimensional computer graphics model. This technique doesn't require any pre-processing nor marker setting but is directly applied to the microscope view and the graphics rendering. Therefore, any special set up in image scanning or preoperative preparation is not necessary.