Pharmacokinetics : Principles and Applications

Chapter 1: Groundwork Chapter 2: General introduction of physiological modeling and compartmental analysis Chapter 3: Routes of administration and drug absorption Chapter 4: Drug distribution Chapter 5: Drug elimination Chapter 6: Linear one-compartment model with instantaneous input and first-order output Chapter 7: Linear one-compartment model with zero-order input and first-order output Chapter 8: Linear one-compartment model with zero-order input and first-order output Chapter 9: Analysis of urinary data Chapter 10: Linear one-compartment model: Multiple Dosing Kinetics Chapter 11: Linear two-compartment model with instantaneous input and first-order output Chapter 12: Linear two-compartment model: Multiple Dosing Kinetics Chapter 13: General approaches of dosage adjustment for patients with renal impairment Chapter 14: Effect of dialysis of pharmacokinetics of drugs Chapter 15: Bioavailability and bioequivalence evaluation Chapter 16: Noncompartmental approach in pharmacokinetics based on statistical moments Appendix A: Answers to assignments