An Introduction to EEG Source Analysis with an Illustration of a Study on Error-Related Potentials

Over the last twenty years, blind source separation (BSS) has become a fundamental signal processing tool in the study of human electroencephalography (EEG), other biological data, as well as in many other signal processing domains such as speech, images, geophysics, and wireless. This chapter introduces a short review of brain volume conduction theory, demonstrating that BSS modeling is grounded on current physiological knowledge. Then, it illustrates a general BSS scheme requiring the estimation of second-order statistics (SOS) only. A simple and efficient implementation based on the approximate joint diagonalization of covariance matrices (AJDC) is described. The method operates in the same way in the time or frequency domain (or both at the same time) and is capable of modeling explicitly physiological and experimental source of variations with remarkable flexibility. Finally, this chapter provides a specific example illustrating the analysis of a new experimental study on error-related potentials.

[1]  D. Pham,et al.  Exploiting source non stationary and coloration in blind source separation , 2002, 2002 14th International Conference on Digital Signal Processing Proceedings. DSP 2002 (Cat. No.02TH8628).

[2]  José del R. Millán,et al.  You Are Wrong! - Automatic Detection of Interaction Errors from Brain Waves , 2005, IJCAI.

[3]  Clemens Brunner,et al.  Nonstationary Brain Source Separation for Multiclass Motor Imagery , 2010, IEEE Transactions on Biomedical Engineering.

[4]  K. R. Ridderinkhof,et al.  Electrophysiological correlates of anterior cingulate function in a go/no-go task: Effects of response conflict and trial type frequency , 2003, Cognitive, affective & behavioral neuroscience.

[5]  Terrence J. Sejnowski,et al.  An Information-Maximization Approach to Blind Separation and Blind Deconvolution , 1995, Neural Computation.

[6]  D. Tucker,et al.  Frontal midline theta and the error-related negativity: neurophysiological mechanisms of action regulation , 2004, Clinical Neurophysiology.

[7]  Arnaud Delorme,et al.  EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis , 2004, Journal of Neuroscience Methods.

[8]  Valer Jurcak,et al.  10/20, 10/10, and 10/5 systems revisited: Their validity as relative head-surface-based positioning systems , 2007, NeuroImage.

[9]  F. L. D. Silva,et al.  Event-related EEG/MEG synchronization and desynchronization: basic principles , 1999, Clinical Neurophysiology.

[10]  Bijan Afsari,et al.  Sensitivity Analysis for the Problem of Matrix Joint Diagonalization , 2008, SIAM J. Matrix Anal. Appl..

[11]  G. Pfurtscheller Central beta rhythm during sensorimotor activities in man. , 1981, Electroencephalography and clinical neurophysiology.

[12]  Marco Congedo,et al.  EEG source analysis in obsessive–compulsive disorder , 2011, Clinical Neurophysiology.

[13]  Ronald Phlypo,et al.  Joint BSS as a natural analysis framework for EEG-hyperscanning , 2013, 2013 IEEE International Conference on Acoustics, Speech and Signal Processing.

[14]  Adrian R. Willoughby,et al.  The Medial Frontal Cortex and the Rapid Processing of Monetary Gains and Losses , 2002, Science.

[15]  J. Cardoso,et al.  Blind beamforming for non-gaussian signals , 1993 .

[16]  J. Hohnsbein,et al.  Effects of crossmodal divided attention on late ERP components. II. Error processing in choice reaction tasks. , 1991, Electroencephalography and clinical neurophysiology.

[17]  Ronald Phlypo,et al.  Orthogonal and non-orthogonal joint blind source separation in the least-squares sense , 2012, 2012 Proceedings of the 20th European Signal Processing Conference (EUSIPCO).

[18]  E. Oja,et al.  Independent Component Analysis , 2013 .

[19]  Paul Van de Heyninga,et al.  Correlation between Independent Components of scalp EEG and intracranial EEG ( iEEG ) time series , 2007 .

[20]  Ricardo Chavarriaga,et al.  EEG error-related potentials detection with a Bayesian filter , 2009, 2009 4th International IEEE/EMBS Conference on Neural Engineering.

[21]  Pierre Comon,et al.  Independent component analysis, A new concept? , 1994, Signal Process..

[22]  R D Pascual-Marqui,et al.  Standardized low-resolution brain electromagnetic tomography (sLORETA): technical details. , 2002, Methods and findings in experimental and clinical pharmacology.

[23]  Christian Jutten,et al.  Space or time adaptive signal processing by neural network models , 1987 .

[24]  J. Hohnsbein,et al.  ERP components on reaction errors and their functional significance: a tutorial , 2000, Biological Psychology.

[25]  Moritz Grosse-Wentrup,et al.  Multiclass Common Spatial Patterns and Information Theoretic Feature Extraction , 2008, IEEE Transactions on Biomedical Engineering.

[26]  Kiyotoshi Matsuoka,et al.  A neural net for blind separation of nonstationary signals , 1995, Neural Networks.

[27]  Jean-Luc Anton,et al.  Region of interest analysis using an SPM toolbox , 2010 .

[28]  Eric Moulines,et al.  A blind source separation technique using second-order statistics , 1997, IEEE Trans. Signal Process..

[29]  C. Braun,et al.  Event-Related Brain Potentials Following Incorrect Feedback in a Time-Estimation Task: Evidence for a Generic Neural System for Error Detection , 1997, Journal of Cognitive Neuroscience.

[30]  Dinh-Tuan Pham,et al.  Approximate Joint Singular Value Decomposition of an Asymmetric Rectangular Matrix Set , 2011, IEEE Transactions on Signal Processing.

[31]  Peter Ullsperger,et al.  Dissociable medial frontal negativities from a common monitoring system for self- and externally caused failure of goal achievement , 2009, NeuroImage.

[32]  M. Fuchs,et al.  A standardized boundary element method volume conductor model , 2002, Clinical Neurophysiology.

[33]  Ernst Fernando Lopes Da Silva Niedermeyer,et al.  Electroencephalography, basic principles, clinical applications, and related fields , 1982 .

[34]  F. H. Lopes da Silva,et al.  Event-related potentials: methodology and quantification , 1998 .

[35]  R. Greenblatt,et al.  Local linear estimators for the bioelectromagnetic inverse problem , 2005, IEEE Transactions on Signal Processing.

[36]  J L Lancaster,et al.  Automated Talairach Atlas labels for functional brain mapping , 2000, Human brain mapping.

[37]  M. Congedo,et al.  Group independent component analysis of resting state EEG in large normative samples. , 2010, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[38]  Karim Abed-Meraim,et al.  A general framework for second-order blind separation of stationary colored sources , 2008, Signal Process..

[39]  E.-J. Speckmann,et al.  Introduction of the neurophysiological basis of the EEG and DC potentials , 1993 .

[40]  Dinh-Tuan Pham,et al.  Blind separation of instantaneous mixtures of nonstationary sources , 2001, IEEE Trans. Signal Process..

[41]  Christian Jutten,et al.  On the blind source separation of human electroencephalogram by approximate joint diagonalization of second order statistics , 2008, Clinical Neurophysiology.

[42]  J D Watson,et al.  Nonparametric Analysis of Statistic Images from Functional Mapping Experiments , 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[43]  G. Buzsáki Rhythms of the brain , 2006 .

[44]  Arie Yeredor,et al.  Second-order methods based on color , 2010 .

[45]  P. Tichavsky,et al.  Fast Approximate Joint Diagonalization Incorporating Weight Matrices , 2009, IEEE Transactions on Signal Processing.

[46]  Jean-Francois Cardoso,et al.  Blind signal separation: statistical principles , 1998, Proc. IEEE.

[47]  John J. B. Allen,et al.  Theta EEG dynamics of the error-related negativity , 2007, Clinical Neurophysiology.

[48]  Christian Jutten,et al.  Blind separation of sources, part I: An adaptive algorithm based on neuromimetic architecture , 1991, Signal Process..

[49]  Moeness G. Amin,et al.  Blind source separation based on time-frequency signal representations , 1998, IEEE Trans. Signal Process..

[50]  T. Ens,et al.  Blind signal separation : statistical principles , 1998 .

[51]  Robert Oostenveld,et al.  FieldTrip: Open Source Software for Advanced Analysis of MEG, EEG, and Invasive Electrophysiological Data , 2010, Comput. Intell. Neurosci..

[52]  J Mazziotta,et al.  A probabilistic atlas and reference system for the human brain: International Consortium for Brain Mapping (ICBM). , 2001, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[53]  F. H. Lopes da Silva,et al.  Biophysical aspects of EEG and magnetoencephalogram generation , 1998 .

[54]  Marco Congedo,et al.  Brain Oscillatory Activity during Spatial Navigation: Theta and Gamma Activity Link Medial Temporal and Parietal Regions , 2012, Journal of Cognitive Neuroscience.

[55]  Pierre Comon,et al.  Handbook of Blind Source Separation: Independent Component Analysis and Applications , 2010 .

[56]  Jason Farquhar,et al.  Interactions Between Pre-Processing and Classification Methods for Event-Related-Potential Classification , 2012, Neuroinformatics.

[57]  Lang Tong,et al.  Waveform-preserving blind estimation of multiple independent sources , 1993, IEEE Trans. Signal Process..

[58]  G. Darmois,et al.  Analyse générale des liaisons stochastiques: etude particulière de l'analyse factorielle linéaire , 1953 .

[59]  Antoine Souloumiac,et al.  Blind source detection and separation using second order non-stationarity , 1995, 1995 International Conference on Acoustics, Speech, and Signal Processing.

[60]  Marco Steinhauser,et al.  Performance monitoring and the causal attribution of errors , 2011, Cognitive, affective & behavioral neuroscience.

[61]  J. Talairach,et al.  Co-Planar Stereotaxic Atlas of the Human Brain: 3-Dimensional Proportional System: An Approach to Cerebral Imaging , 1988 .

[62]  J. Sarvas Basic mathematical and electromagnetic concepts of the biomagnetic inverse problem. , 1987, Physics in medicine and biology.

[63]  D. Meyer,et al.  A Neural System for Error Detection and Compensation , 1993 .

[64]  Pierre Brémaud Fourier Analysis of Time Series , 2014 .

[65]  Schuster,et al.  Separation of a mixture of independent signals using time delayed correlations. , 1994, Physical review letters.

[66]  M. Herrmann,et al.  Source localization (LORETA) of the error-related-negativity (ERN/Ne) and positivity (Pe). , 2004, Brain research. Cognitive brain research.

[67]  S. S. Young,et al.  Resampling-Based Multiple Testing: Examples and Methods for p-Value Adjustment , 1993 .