Reviewing model application to support animal health decision making.

Animal health is of societal importance as it affects human welfare, and anthropogenic interests shape decision making to assure animal health. Scientific advice to support decision making is manifold. Modelling, as one piece of the scientific toolbox, is appreciated for its ability to describe and structure data, to give insight in complex processes and to predict future outcome. In this paper we study the application of scientific modelling to support practical animal health decisions. We reviewed the 35 animal health related scientific opinions adopted by the Animal Health and Animal Welfare Panel of the European Food Safety Authority (EFSA). Thirteen of these documents were based on the application of models. The review took two viewpoints, the decision maker's need and the modeller's approach. In the reviewed material three types of modelling questions were addressed by four specific model types. The correspondence between tasks and models underpinned the importance of the modelling question in triggering the modelling approach. End point quantifications were the dominating request from decision makers, implying that prediction of risk is a major need. However, due to knowledge gaps corresponding modelling studies often shed away from providing exact numbers. Instead, comparative scenario analyses were performed, furthering the understanding of the decision problem and effects of alternative management options. In conclusion, the most adequate scientific support for decision making - including available modelling capacity - might be expected if the required advice is clearly stated.

[1]  Steven F. Railsback,et al.  Individual-based modeling and ecology , 2005 .

[2]  M. G. Garner,et al.  Evaluating the effectiveness of early vaccination in the control and eradication of equine influenza--a modelling approach. , 2011, Preventive veterinary medicine.

[3]  A. W. Jalvingh,et al.  Evaluating control strategies for outbreaks in BHV1-free areas using stochastic and spatial simulation. , 2000, Preventive veterinary medicine.

[4]  R. Durrett,et al.  From individuals to epidemics. , 1996, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[5]  Camille Szmaragd,et al.  The Spread of Bluetongue Virus Serotype 8 in Great Britain and Its Control by Vaccination , 2010, PloS one.

[6]  Thomas Fent,et al.  Agent-Based Computational Modelling: Applications in Demography, Social, Economic and Environmental Sciences , 2006 .

[7]  A. Hill,et al.  The North American Animal Disease Spread Model: a simulation model to assist decision making in evaluating animal disease incursions. , 2007, Preventive veterinary medicine.

[8]  P A J Martin,et al.  Demonstrating freedom from disease using multiple complex data sources 1: a new methodology based on scenario trees. , 2007, Preventive veterinary medicine.

[9]  R. May,et al.  Modelling vaccination strategies against foot-and-mouth disease , 2003, Nature.

[10]  Uta Berger,et al.  Pattern-Oriented Modeling of Agent-Based Complex Systems: Lessons from Ecology , 2005, Science.

[11]  S. Rushton,et al.  Investigating the spatial dynamics of bovine tuberculosis in badger populations: evaluating an individual-based simulation model , 2003 .

[12]  M. D. de Jong,et al.  Modelling the effectiveness and risks of vaccination strategies to control classical swine fever epidemics , 2009, Journal of The Royal Society Interface.

[13]  Benjamin M. Bolker,et al.  Ecological Models and Data in R , 2008 .

[14]  Volker Grimm,et al.  Ecological models supporting environmental decision making: a strategy for the future. , 2010, Trends in ecology & evolution.

[15]  M. S. Sánchez,et al.  Should we expect population thresholds for wildlife disease? , 2005, Trends in ecology & evolution.

[16]  S. Harris,et al.  Rabies in urban foxes (Vulpes vulpes) in Britain: the use of a spatial stochastic simulation model to examine the pattern of spread and evaluate the efficacy of different control régimes. , 1991, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[17]  Birgit Müller,et al.  A standard protocol for describing individual-based and agent-based models , 2006 .

[18]  T. Selhorst,et al.  Emergency vaccination of rabies under limited resources – combating or containing? , 2005, BMC infectious diseases.

[19]  Nick Taylor,et al.  Review of the use of models in informing disease control policy development and adjustment. , 2003 .

[20]  M Sculpher,et al.  Health Technology Assessment: Development and Future , 2009 .

[21]  S. Nielsen,et al.  A stochastic model simulating paratuberculosis in a dairy herd. , 2007, Preventive veterinary medicine.

[22]  D. Augustine Modelling Chlamydia–koala interactions: coexistence, population dynamics and conservation implications , 1998 .

[23]  John E. Gross,et al.  Chronic wasting disease in mule deer: disease dynamics and control. , 2001 .

[24]  Stephanie Kramer-Schadt,et al.  Individual variations in infectiousness explain long‐term disease persistence in wildlife populations , 2009 .

[25]  V. Grimm,et al.  Ecological Models in Support of Regulatory Risk Assessments of Pesticides: Developing a Strategy for the Future , 2009, Integrated environmental assessment and management.

[26]  Steven F. Railsback,et al.  Agent-Based Models in Ecology: Patterns and Alternative Theories of Adaptive Behaviour , 2006 .

[27]  H. Scott Hurd,et al.  The application of simulation models and systems analysis in epidemiology: a review , 1993 .

[28]  A. Murray A model of the emergence of infectious pancreatic necrosis virus in Scottish salmon farms 1996–2003 , 2006 .

[29]  M Alan Brookhart,et al.  Disease transmission models for public health decision making: analysis of epidemic and endemic conditions caused by waterborne pathogens. , 2002, Environmental health perspectives.

[30]  A. W. Jalvingh,et al.  Spatial and stochastic simulation to compare two emergency-vaccination strategies with a marker vaccine in the 1997/1998 Dutch Classical Swine Fever epidemic. , 2001, Preventive veterinary medicine.

[31]  Roy M. Anderson,et al.  Population dynamics of fox rabies in Europe , 1981, Nature.

[32]  L Tischendorf,et al.  Chance and risk of controlling rabies in large–scale and long–term immunized fox populations , 1998, Proceedings of the Royal Society of London. Series B: Biological Sciences.