PharmaNet: Pharmaceutical discovery with deep recurrent neural networks
暂无分享,去创建一个
Pablo Arbeláez | Cristina González | Natalia Valderrama | Paola Ruiz Puentes | Laura Daza | Carolina Muñoz-Camargo | Juan C. Cruz | P. Arbeláez | Cristina González | L. Daza | Carolina Muñoz-Camargo | Natalia Valderrama
[1] Sergey Ivanov,et al. DIGEP-Pred: web service for in silico prediction of drug-induced gene expression profiles based on structural formula , 2013, Bioinform..
[2] A. Berghuis,et al. Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase. , 2015, Bioorganic & medicinal chemistry letters.
[3] Manfred Kansy,et al. High throughput solubility measurement in drug discovery and development. , 2007, Advanced drug delivery reviews.
[4] Luc Van Gool,et al. Deep Retinal Image Understanding , 2016, MICCAI.
[5] C. Humblet,et al. Idea2Data: Toward a New Paradigm for Drug Discovery. , 2019, ACS medicinal chemistry letters.
[6] M. Notarnicola,et al. Deregulated expression and activity of Farnesyl Diphosphate Synthase (FDPS) in Glioblastoma , 2017, Scientific Reports.
[7] Y. Tsantrizos,et al. Inhibition of farnesyl pyrophosphate (FPP) and/or geranylgeranyl pyrophosphate (GGPP) biosynthesis and its implication in the treatment of cancers , 2019, Critical reviews in biochemistry and molecular biology.
[8] Luc Van Gool,et al. The Pascal Visual Object Classes Challenge: A Retrospective , 2014, International Journal of Computer Vision.
[9] M. Kansy,et al. 'Flexible-acceptor' General Solubility Equation for 'beyond Rule of 5' Drugs. , 2020, Molecular pharmaceutics.
[10] Geoffrey E. Hinton,et al. ImageNet classification with deep convolutional neural networks , 2012, Commun. ACM.
[11] Andreas Persidis,et al. Artificial intelligence for drug design , 1997, Nature Biotechnology.
[12] Konstantinos Kamnitsas,et al. Fast Fully Automatic Segmentation of the Human Placenta from Motion Corrupted MRI , 2016, MICCAI.
[13] Jitendra Malik,et al. Learning to detect natural image boundaries using local brightness, color, and texture cues , 2004, IEEE Transactions on Pattern Analysis and Machine Intelligence.
[14] L. Kastl,et al. miRNA-34a is associated with docetaxel resistance in human breast cancer cells , 2011, Breast Cancer Research and Treatment.
[15] Keith C. C. Chan,et al. Large-scale prediction of drug-target interactions from deep representations , 2016, 2016 International Joint Conference on Neural Networks (IJCNN).
[16] Behzad Baradaran,et al. The Different Mechanisms of Cancer Drug Resistance: A Brief Review , 2017, Advanced pharmaceutical bulletin.
[17] B. Vincenzi,et al. Bisphosphonates as anticancer agents in early breast cancer: preclinical and clinical evidence , 2015, Breast Cancer Research.
[18] Tyler E. Miller,et al. MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27Kip1*♦ , 2008, Journal of Biological Chemistry.
[19] Derek Hoiem,et al. Diagnosing Error in Object Detectors , 2012, ECCV.
[20] Izhar Wallach,et al. AtomNet: A Deep Convolutional Neural Network for Bioactivity Prediction in Structure-based Drug Discovery , 2015, ArXiv.
[21] Ji Hoon Jeon,et al. Farnesyl diphosphate synthase is important for the maintenance of glioblastoma stemness , 2018, Experimental & Molecular Medicine.
[22] P. Sanseau,et al. Drug repurposing: progress, challenges and recommendations , 2018, Nature Reviews Drug Discovery.
[23] Thierry Kogej,et al. Generating Focused Molecule Libraries for Drug Discovery with Recurrent Neural Networks , 2017, ACS central science.
[24] Jakub M. Tomczak,et al. Interaction prediction in structure-based virtual screening using deep learning , 2018, Comput. Biol. Medicine.
[25] M. Clemons,et al. Adjuvant bisphosphonate treatment for breast cancer: Where are we heading and can the pre-clinical literature help us get there? , 2012, Journal of bone oncology.
[26] Emma J. Chory,et al. A Deep Learning Approach to Antibiotic Discovery , 2020, Cell.
[27] Sharangdhar S. Phatak,et al. High-throughput and in silico screenings in drug discovery , 2009, Expert opinion on drug discovery.
[28] A. Berghuis,et al. Human isoprenoid synthase enzymes as therapeutic targets , 2014, Front. Chem..
[29] Jitendra Malik,et al. A database of human segmented natural images and its application to evaluating segmentation algorithms and measuring ecological statistics , 2001, Proceedings Eighth IEEE International Conference on Computer Vision. ICCV 2001.
[30] Vladimir Poroikov,et al. QSAR Modelling of Rat Acute Toxicity on the Basis of PASS Prediction , 2011, Molecular informatics.
[31] Xiuping Liu,et al. Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells. , 2008, Biochemical pharmacology.
[32] Abhinav Vishnu,et al. SMILES2Vec: An Interpretable General-Purpose Deep Neural Network for Predicting Chemical Properties , 2017, ArXiv.
[33] Pablo Andrés Arbeláez,et al. ISINet: An Instance-Based Approach for Surgical Instrument Segmentation , 2020, MICCAI.
[34] Jugal K. Kalita,et al. Deep Learning applied to NLP , 2017, ArXiv.
[35] Qing Liu,et al. miR-29c contribute to glioma cells temozolomide sensitivity by targeting O6-methylguanine-DNA methyltransferases indirectly , 2016, Oncotarget.
[36] A. Addario,et al. Role of microRNAs in drug-resistant ovarian cancer cells. , 2008, Gynecologic oncology.
[37] Gerard D. Wright,et al. Expanding the soil antibiotic resistome: exploring environmental diversity. , 2007, Current opinion in microbiology.
[38] J. Choubey,et al. Insilico Docking Analysis of Nitrogen Containing Bisphosphonate with Human Fernasyl Pyrophosphate Synthase , 2013 .
[39] Jitendra Malik,et al. Hypercolumns for object segmentation and fine-grained localization , 2014, 2015 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).
[40] F. Lombardo,et al. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. , 2001, Advanced drug delivery reviews.
[41] N. Shomron,et al. Restoration of miR-424 suppresses BCR-ABL activity and sensitizes CML cells to imatinib treatment. , 2015, Cancer letters.
[42] Edward W. Lowe,et al. Computational Methods in Drug Discovery , 2014, Pharmacological Reviews.
[43] Guigang Zhang,et al. Deep Learning , 2016, Int. J. Semantic Comput..
[44] Yoshua Bengio,et al. Learning Phrase Representations using RNN Encoder–Decoder for Statistical Machine Translation , 2014, EMNLP.
[45] Raymond R Tice,et al. Genetic toxicology in silico protocol. , 2019, Regulatory toxicology and pharmacology : RTP.
[46] Viktor Hornak,et al. Hidden bias in the DUD-E dataset leads to misleading performance of deep learning in structure-based virtual screening , 2019, PloS one.
[47] Jakub M. Tomczak,et al. Learning Deep Architectures for Interaction Prediction in Structure-based Virtual Screening , 2016, ArXiv.
[48] C. L. Ventola. The antibiotic resistance crisis: part 1: causes and threats. , 2015, P & T : a peer-reviewed journal for formulary management.
[49] Julian Fierrez,et al. Exploring Recurrent Neural Networks for On-Line Handwritten Signature Biometrics , 2018, IEEE Access.
[50] W. Ko,et al. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges , 2020, International Journal of Antimicrobial Agents.
[51] Pietro Perona,et al. Microsoft COCO: Common Objects in Context , 2014, ECCV.
[52] C. Xiao,et al. MicroRNA-221 Induces Cell Survival and Cisplatin Resistance through PI3K/Akt Pathway in Human Osteosarcoma , 2013, PloS one.
[53] Günter Klambauer,et al. DeepTox: Toxicity Prediction using Deep Learning , 2016, Front. Environ. Sci..
[54] Peter Cresswell,et al. The interferon-inducible protein viperin inhibits influenza virus release by perturbing lipid rafts. , 2007, Cell host & microbe.
[55] Jian Sun,et al. Deep Residual Learning for Image Recognition , 2015, 2016 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).
[56] David Weininger,et al. SMILES. 2. Algorithm for generation of unique SMILES notation , 1989, J. Chem. Inf. Comput. Sci..
[57] G. Schneider,et al. Concepts of Artificial Intelligence for Computer-Assisted Drug Discovery. , 2019, Chemical reviews.
[58] Udo Oppermann,et al. The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants☆ , 2015, Bone.
[59] Wenpeng Yin,et al. Comparative Study of CNN and RNN for Natural Language Processing , 2017, ArXiv.
[60] Lynette M. Smith,et al. FDPS cooperates with PTEN loss to promote prostate cancer progression through modulation of small GTPases/AKT axis , 2019, Oncogene.