Modeling the Sensory Computations of the Olfactory Bulb

Two models are presented as examples to discuss the computational tasks, sensory environments, and computational mechanisms in early olfactory processing. One model proposes that the odor inputs during a sniff cycle are detected and coded by the emergence of odor-dependent and coherent neural oscillatory patterns observed in the mammalian bulb, and that the odor mixtures are segmented by the selective olfactory adaptation to the preexisting and detected odors. The other model argues that the early olfactory processing is to separate the odor mixtures in the input environment into individual odor sources before the odor identities are known, and proposes a fast synaptic learning algorithm that uses the temporal fluctuation structures in the receptor cells for source separation.

[1]  G. M. Dyson The Chemical Senses , 1946, Nature.

[2]  R. Axel,et al.  A novel multigene family may encode odorant receptors: A molecular basis for odor recognition , 1991, Cell.

[3]  G M Shepherd,et al.  Principles of specificity and redundancy underlying the organization of the olfactory system , 1993, Microscopy research and technique.

[4]  Zhaoping Li,et al.  What does post-adaptation color appearance reveal about cortical color representation? , 1993, Vision Research.

[5]  Georg v. Békésy,et al.  OLFACTORY ANALOGUE TO DIRECTIONAL HEARING. , 1964 .

[6]  Michael E. Hasselmo,et al.  Acetylcholine and Learning in a Cortical Associative Memory , 1993, Neural Computation.

[7]  Jelle Atema,et al.  Across-fiber patterns may contain a sensory code for stimulus intensity , 1991, Brain Research Bulletin.

[8]  Alan Gelperin,et al.  Differential conditioning to a compound stimulus and its components in the terrestrial mollusc Limax maximus.. , 1989 .

[9]  D. G. Laing,et al.  Selective attention and the perceptual analysis of odor mixtures , 1992, Physiology & Behavior.

[10]  J S Kauer,et al.  Mapping of odor-related neuronal activity in the olfactory bulb by high-resolution 2-deoxyglucose autoradiography. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[11]  J. Murlis,et al.  Fine‐scale structure of odour plumes in relation to insect orientation to distant pheromone and other attractant sources , 1981 .

[12]  Trygg Engen,et al.  The perception of odors , 1982 .

[13]  W. Freeman Spatial properties of an EEG event in the olfactory bulb and cortex. , 1978, Electroencephalography and clinical neurophysiology.

[14]  M. A. Rogers,et al.  Principles of Neural Science, 2nd ed , 1987 .

[15]  Remo Guidieri Res , 1995, RES: Anthropology and Aesthetics.

[16]  Colin Blakemore,et al.  Vision: Coding and Efficiency , 1991 .

[17]  M. Alexander,et al.  Principles of Neural Science , 1981 .

[18]  J J Hopfield,et al.  Olfactory computation and object perception. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[19]  James M. Bower,et al.  Computation and Neural Systems , 2014, Springer US.

[20]  Joel L. Davis,et al.  Olfaction: A Model System for Computational Neuroscience , 1991 .

[21]  Françoise Fogelman-Soulié,et al.  Disordered Systems and Biological Organization , 1986, NATO ASI Series.

[22]  M. Webster,et al.  Changes in colour appearance following post-receptoral adaptation , 1991, Nature.

[23]  Hans Liljenström Modeling the Dynamics of Olfactory Cortex Using Simplified Network Units and Realistic Architecture , 1991, Int. J. Neural Syst..

[24]  W J Freeman,et al.  Relation of olfactory EEG to behavior: factor analysis. , 1987, Behavioral neuroscience.

[25]  W. Singer,et al.  Oscillatory responses in cat visual cortex exhibit inter-columnar synchronization which reflects global stimulus properties , 1989, Nature.

[26]  D. Tank,et al.  Odour-modulated collective network oscillations of olfactory interneurons in a terrestrial mollusc , 1990, Nature.

[27]  D. G. Laing Olfactory Adaptation in the Rat , 1975 .

[28]  Gérard Dreyfus,et al.  Computational Diversity in a Formal Model of the Insect Olfactory Macroglomerulus , 1993, Neural Computation.

[29]  Stuart Firestein Olfaction: A Model System for Computational Neuroscience. Proceedings of a Conference Held at Wellesley College, 17-18 May 1990. Joel L. Davis , Howard Eichenbaum , 1993 .

[30]  D. Stoddart The Ecology of Vertebrate Olfaction , 1980, Springer Netherlands.

[31]  W. Precht The synaptic organization of the brain G.M. Shepherd, Oxford University Press (1975). 364 pp., £3.80 (paperback) , 1976, Neuroscience.

[32]  G. Shepherd,et al.  Responses of olfactory receptor cells to step pulses of odour at different concentrations in the salamander. , 1978, The Journal of physiology.

[33]  F. Macrides,et al.  Topographic organization of connections between the main olfactory bulb and pars externa of the anterior olfactory nucleus in the hamster , 1984, The Journal of comparative neurology.

[34]  Richard Durbin,et al.  The computing neuron , 1989 .

[35]  R. H. Wright,et al.  The science of smell , 1964 .

[36]  G. Shepherd The Synaptic Organization of the Brain , 1979 .

[37]  B J Richmond,et al.  Concurrent processing and complexity of temporally encoded neuronal messages in visual perception. , 1991, Science.

[38]  H. Panhuber,et al.  Effects of long duration odor exposure on the unit activity of olfactory bulb cells in awake rabbits , 1982, Brain Research.

[39]  W. Freeman,et al.  Spatial EEG patterns, non-linear dynamics and perception: the neo-sherringtonian view , 1985, Brain Research Reviews.

[40]  E. Land The retinex theory of color vision. , 1977, Scientific American.

[41]  W. Freeman,et al.  Changes in spatial patterns of rabbit olfactory EEG with conditioning to odors. , 1982, Psychophysiology.

[42]  Wenner-Grenska samfundet,et al.  Olfaction and taste , 1963 .