Karl H. Clodfelter

发表

PRECISE: a Database of Predicted and Consensus Interaction Sites in Enzymes

Sandor Vajda, Shu-Hsien Sheu, David R. Lancia, 2005, Nucleic Acids Res..

Predictome: a database of putative functional links between proteins

Charles DeLisi, Julian Mintseris, Itai Yanai, 2002, Nucleic Acids Res..

Identification of substrate binding sites in enzymes by computational solvent mapping.

Karl H. Clodfelter, M. Silberstein, S. Dennis, 2003, Journal of molecular biology.

Computational solvent mapping reveals the importance of local conformational changes for broad substrate specificity in mammalian cytochromes P450.

Karl H. Clodfelter, S. Vajda, D. Waxman, 2006, Biochemistry.

Optimal clustering for detecting near-native conformations in protein docking.

Dima Kozakov, Sandor Vajda, Karl H. Clodfelter, 2005, Biophysical journal.

Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).

Karl H. Clodfelter, P. Bauer, N. Kley, 2013, Bioorganic & medicinal chemistry letters.

Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties.

Yang Xiao, Lei Zhang, Karl H. Clodfelter, 2013, Bioorganic & medicinal chemistry letters.

Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (Nampt) inhibitors.

Karl H. Clodfelter, Zhongguo Wang, Mark Zak, 2013, Journal of medicinal chemistry.

Sexual dimorphism of rat liver gene expression: regulatory role of growth hormone revealed by deoxyribonucleic Acid microarray analysis.

Karl H. Clodfelter, D. Waxman, A. Ahluwalia, 2004, Molecular endocrinology.

Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis.

Karl H. Clodfelter, P. Hodor, D. Waxman, 2006, Molecular endocrinology.

upon STAT5b: STAT5b-dependent Activation of Male Genes and Repression of Female Genes Revealed by Microarray Analysis *

Karl H. Clodfelter, P. Hodor, D. Waxman, 2006 .

Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis.

Karl H. Clodfelter, P. Hodor, D. Waxman, 2007, Physiological genomics.

Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility.

Karl H. Clodfelter, N. Skelton, D. Sampath, 2015, Bioorganic & medicinal chemistry letters.

Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors.

Karl H. Clodfelter, Zhongguo Wang, Mark Zak, 2013, Bioorganic & medicinal chemistry letters.

Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitors.

Karl H. Clodfelter, P. Bauer, N. Kley, 2013, Journal of medicinal chemistry.