M. Dudley

S. Rosenberg, C. Van Waes, R. Morgan, 2011, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

Antigensof Autologous Melanoma Glycoprotein 100 and Does Not Alter the Recognition of Melanoma Tumor Antigen Primary Human Lymphocytes Affords Avid High Efficiency TCR Gene Transfer into

S. Rosenberg, P. Robbins, N. Restifo, 2013 .

regression and targets normal tissues expressing cognate antigen Gene therapy with human and mouse T-cell receptors mediates cancer

S. Rosenberg, Alexandria P. Cogdill, R. Morgan, 2009 .

High Efficiency TCR Gene Transfer into Primary Human Lymphocytes Affords Avid Recognition of Melanoma Tumor Antigen Glycoprotein 100 and Does Not Alter the Recognition of Autologous Melanoma Antigens

S. Rosenberg, R. Morgan, P. Robbins, 2003, The Journal of Immunology.

Adoptive cell therapy for patients with melanoma, using tumor-infiltrating lymphocytes genetically engineered to secrete interleukin-2.

S. Rosenberg, R. Morgan, K. Matsuda, 2008, Human gene therapy.

Tumor Infiltrating Lymphocyte Therapy for Metastatic Melanoma: Analysis of Tumors Resected for TIL

S. Steinberg, S. Rosenberg, J. Yang, 2010, Journal of immunotherapy.

Effective Treatment Of Chemotherapy-Refractory Diffuse Large B-Cell Lymphoma With Autologous T Cells Genetically-Engineered To Express An Anti-CD19 Chimeric Antigen Receptor

Sadik H. Kassim, S. Rosenberg, J. Yang, 2013 .

Donor-Derived Anti-CD19 Chimeric-Antigen-Receptor-Expressing T Cells Cause Regression Of Malignancy Persisting After Allogeneic Hematopoietic Stem Cell Transplantation

Sadik H. Kassim, W. Telford, S. Rosenberg, 2013 .

Evaluation of &ggr;-Retroviral Vectors That Mediate the Inducible Expression of IL-12 for Clinical Application

S. Rosenberg, R. Morgan, M. Dudley, 2012, Journal of immunotherapy.

Successful Treatment of Melanoma Brain Metastases with Adoptive Cell Therapy

S. Rosenberg, J. Butman, J. Yang, 2010, Clinical Cancer Research.

Impact of a recombinant fowlpox vaccine on the efficacy of adoptive cell therapy with tumor infiltrating lymphocytes in a patient with metastatic melanoma.

S. Rosenberg, M. Dudley, J. Wunderlich, 2009, Journal of immunotherapy.

B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells.

W. Wilson, S. Rosenberg, R. Morgan, 2012, Blood.

A major player "gets in the act".

M. Dudley, 2012, Journal of immunotherapy.

Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor.

Sadik H. Kassim, M. Raffeld, S. Rosenberg, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Persistence of CTL Clones Targeting Melanocyte Differentiation Antigens Was Insufficient to Mediate Significant Melanoma Regression in Humans

A. K. Srivastava, S. Rosenberg, J. Yang, 2014, Clinical Cancer Research.

Adoptive Cell Therapy for Patients with Melanoma

M. Dudley, 2011, Journal of Cancer.

Cancer immunotherapy.

S. Rosenberg, N. Restifo, M. Dudley, 2008, The New England journal of medicine.

Adoptive cell transfer therapy.

S. Rosenberg, M. Dudley, 2007, Seminars in oncology.

Warrior, miscreant, suicide: making better killers

M. Dudley, 2007 .

Lymphodepletion Patients with Metastatic Melanoma following Peripheral Blood Mononuclear Cells to Adoptive Transfer of Vaccine-Induced

S. Rosenberg, D. Powell, M. Dudley, 2006 .

Adoptive Transfer of Vaccine-Induced Peripheral Blood Mononuclear Cells to Patients with Metastatic Melanoma following Lymphodepletion1

S. Rosenberg, D. Powell, M. Dudley, 2006, The Journal of Immunology.

Persistence of Multiple Tumor-Specific T-Cell Clones Is Associated with Complete Tumor Regression in a Melanoma Patient Receiving Adoptive Cell Transfer Therapy

S. Rosenberg, P. Robbins, M. Dudley, 2005, Journal of immunotherapy.

Transition of late-stage effector T cells to CD27+ CD28+ tumor-reactive effector memory T cells in humans after adoptive cell transfer therapy.

S. Rosenberg, D. Powell, P. Robbins, 2005, Blood.

Transfer Therapy Cancer Regression in Patients Receiving Cell Lymphocyte Clonotypes Correlates with Cutting Edge: Persistence of Transferred

S. Rosenberg, D. Powell, P. Robbins, 2004 .

TherapyImplications for Adoptive Cell Transfer Gastrointestinal Cancers and Melanoma: Infiltrating Visceral Metastases from Phenotype and Function of T Cells

S. Rosenberg, S. Turcotte, E. Tran, 2013 .

Levels of peripheral CD4(+)FoxP3(+) regulatory T cells are negatively associated with clinical response to adoptive immunotherapy of human cancer.

S. Steinberg, S. Rosenberg, D. Schrump, 2012, Blood.

T-cell clones from melanoma patients immunized against an anchor-modified gp100 peptide display discordant effector phenotypes.

S. Rosenberg, M. Dudley, J. Wunderlich, 2000, Cancer journal.

Efficient Chromosomal Mapping of a Methylcholanthrene- Induced Tumor Antigen by CTL Immunoselection1

S. Akilesh, D. Roopenian, M. Dudley, 2001, The Journal of Immunology.

Kinetics of TCR Use in Response to Repeated Epitope-Specific Immunization

F. Marincola, S. Rosenberg, E. Wang, 2001, The Journal of Immunology.

Functional Heterogeneity of Vaccine-Induced CD8+ T Cells1

F. Marincola, S. Rosenberg, E. Wang, 2002, The Journal of Immunology.

TCR stimulation protects CD8+ T cells from CD95 mediated apoptosis.

D. Leroith, M. Karas, S. Yakar, 2001, Human immunology.

Antitumor immunization with a minimal peptide epitope (G9-209-2M) leads to a functionally heterogeneous CTL response.

S. Rosenberg, M. Nishimura, M. Dudley, 1999, Journal of immunotherapy.

Myeloid Cells Obtained from the Blood but Not from the Tumor Can Suppress T-cell Proliferation in Patients with Melanoma

S. Rosenberg, S. Turcotte, M. Dudley, 2012, Clinical Cancer Research.

95 Inhibition of AKT signaling during expansion of TCR-engineered T-cells from patient leukocyte material generates SPEAR T-cells with enhanced functional potential in vitro

M. Dudley, J. Silk, K. Miller, 2020, Journal for ImmunoTherapy of Cancer.

Multiple HLA Class II-Restricted Melanocyte Differentiation Antigens Are Recognized by Tumor-Infiltrating Lymphocytes from a Patient with Melanoma

S. Rosenberg, G. Zeng, P. Robbins, 2002, The Journal of Immunology.

Patient with Melanoma Tumor-Infiltrating Lymphocytes from a Differentiation Antigens Are Recognized by Multiple HLA Class II-Restricted Melanocyte

S. Rosenberg, P. Robbins, M. Dudley, 2002 .

Loss of a unique tumor antigen by cytotoxic T lymphocyte immunoselection from a 3-methylcholanthrene-induced mouse sarcoma reveals secondary unique and shared antigens

D. Roopenian, M. Dudley, 1996, The Journal of experimental medicine.

Antitumor Efficacy Demonstrate Superior In Vitro and In Vivo High Avidity CTLs for Two Self-Antigens

S. Rosenberg, J. Yang, H. Zeh, 1998 .

Survival, Persistence, and Progressive Differentiation of Adoptively Transferred Tumor-Reactive T Cells Associated with Tumor Regression

S. Rosenberg, P. Robbins, M. Dudley, 2005, Journal of immunotherapy.

Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma.

S. Rosenberg, J. Yang, S. Topalian, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Transfer Therapy Cancer Regression in Patients Receiving Cell Lymphocyte Clonotypes Correlates with Cutting Edge: Persistence of Transferred

S. Rosenberg, D. Powell, P. Robbins, 2022 .

MHC Class I-Mediated Antigen Presentation and Induction of CD8+ Cytotoxic T-Cell Responses in Autoimmune Diabetes-Prone NOD Mice

E. Leiter, D. Roopenian, K. Croitoru, 1996, Diabetes.

Adoptive-cell-transfer therapy for the treatment of patients with cancer

Steven A. Rosenberg, S. Rosenberg, M. Dudley, 2003, Nature Reviews Cancer.

Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired.

S. Rosenberg, D. White, M. Dudley, 2009, Blood.

CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2

R. Simon, F. Marincola, S. Rosenberg, 2013, British Journal of Cancer.

Ocular and systemic autoimmunity after successful tumor-infiltrating lymphocyte immunotherapy for recurrent, metastatic melanoma.

S. Rosenberg, W. Wong, R. Nussenblatt, 2009, Ophthalmology.

A Pilot Trial Using Lymphocytes Genetically Engineered with an NY-ESO-1–Reactive T-cell Receptor: Long-term Follow-up and Correlates with Response

Sadik H. Kassim, M. Raffeld, S. Rosenberg, 2014, Clinical Cancer Research.

Simplified Method of the Growth of Human Tumor Infiltrating Lymphocytes in Gas-permeable Flasks to Numbers Needed for Patient Treatment

Marianna Sabatino, S. Rosenberg, M. Sabatino, 2012, Journal of immunotherapy.

Generation of Tumor-Infiltrating Lymphocyte Cultures for Use in Adoptive Transfer Therapy for Melanoma Patients

Steven A. Rosenberg, S. Rosenberg, J. Even, 2003, Journal of immunotherapy.

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen.

S. Rosenberg, Alexandria P. Cogdill, R. Morgan, 2009, Blood.

Single-cell multiplexed cytokine profiling of CD19 CAR-T cells reveals a diverse landscape of polyfunctional antigen-specific response

Alaina Kaiser, Rong Fan, Patrick Paczkowski, 2017, Journal of Immunotherapy for Cancer.

PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors.

D. Douek, S. Rosenberg, S. Darko, 2014, The Journal of clinical investigation.

Efficient Identification of Mutated Cancer Antigens Recognized by T Cells Associated with Durable Tumor Regressions

S. Rosenberg, Y. Samuels, J. Yang, 2014, Clinical Cancer Research.

Adoptive cell therapy for the treatment of patients with metastatic melanoma.

S. Rosenberg, M. Dudley, 2009, Current opinion in immunology.

Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation.

Sadik H. Kassim, W. Telford, S. Rosenberg, 2013, Blood.

Genetic analysis of Rhizobium-plant interactions

N. Peters, M. Dudley, S. Long, 1986 .

Mutated PPP1R3B Is Recognized by T Cells Used To Treat a Melanoma Patient Who Experienced a Durable Complete Tumor Regression

D. Douek, S. Rosenberg, Y. Samuels, 2013, The Journal of Immunology.

Minimally Cultured Tumor-infiltrating Lymphocytes Display Optimal Characteristics for Adoptive Cell Therapy

S. Rosenberg, P. Robbins, M. Dudley, 2008, Journal of immunotherapy.

IRF5 gene polymorphisms in melanoma

F. Marincola, R. Simon, S. Rosenberg, 2012, Journal of Translational Medicine.

Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1.

M. Raffeld, S. Rosenberg, R. Morgan, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Randomized selection design trial evaluating CD8+-enriched versus unselected tumor-infiltrating lymphocytes for adoptive cell therapy for patients with melanoma.

Seth M Steinberg, S. Steinberg, S. Rosenberg, 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Relationship of p53 overexpression on cancers and recognition by anti-p53 T cell receptor-transduced T cells.

S. Rosenberg, D. Powell, R. Morgan, 2008, Human gene therapy.

Frequency and histological appearance of adenomas in multiple intestinal neoplasia mice are unaffected by severe combined immunodeficiency (scid) mutation

D. Roopenian, M. Dudley, J. Sundberg, 1996, International journal of cancer.

Replication-competent retroviruses in gene-modified T cells used in clinical trials: is it time to revise the testing requirements?

S. Shurtleff, K. Cornetta, S. Rosenberg, 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

379 Initial safety, efficacy, and product attributes from the SURPASS trial with ADP-A2M4CD8, a SPEAR T-cell therapy incorporating an affinity optimized TCR targeting MAGE-A4 and a CD8α co-receptor

D. Hong, P. Fracasso, S. Saibil, 2020 .

Complete regression of metastatic cervical cancer after treatment with human papillomavirus-targeted tumor-infiltrating T cells.

S. Rosenberg, J. Yang, N. Restifo, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Clinical-scale selection and viral transduction of human naïve and central memory CD8+ T cells for adoptive cell therapy of cancer patients

A. Scheffold, S. Rosenberg, M. Dudley, 2013, Cancer Immunology, Immunotherapy.

A non-nodulating alfalfa mutant displays neither root hair curling nor early cell division in response to Rhizobium meliloti.

M. Dudley, S. Long, 1989, The Plant cell.

Microscopic studies of cell divisions induced in alfalfa roots by Rhizobium meliloti

M. Dudley, S. Long, T. Jacobs, 1987, Planta.

New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancer

F. Marincola, J. Heath, S. Rosenberg, 2012, Journal of Translational Medicine.

Bioreactors get personal

M. Dudley, R. Somerville, Mark E. Dudley, 2012, Oncoimmunology.

Clinical scale rapid expansion of lymphocytes for adoptive cell transfer therapy in the WAVE® bioreactor

S. Rosenberg, M. Dudley, M. Parkhurst, 2012, Journal of Translational Medicine.

Epitope-Specific Immunization Kinetics of TCR Use in Response to Repeated

Steven A. Rosenberg, Francesco M. Marincola, Mark E. Dudley, 2013 .

976TiP SPEARHEAD-2 trial design: A phase II pilot trial of ADP-A2M4 in combination with pembrolizumab in patients with recurrent or metastatic head and neck cancer

E. Cohen, M. Dudley, M. Gibson, 2020 .

Gene Transfer of Tumor-Reactive TCR Confers Both High Avidity and Tumor Reactivity to Nonreactive Peripheral Blood Mononuclear Cells and Tumor-Infiltrating Lymphocytes1

S. Rosenberg, D. Powell, R. Morgan, 2006, The Journal of Immunology.

A Pilot Trial of the Combination of Vemurafenib with Adoptive Cell Therapy in Patients with Metastatic Melanoma

S. Rosenberg, M. Dudley, J. Wunderlich, 2016, Clinical Cancer Research.

Tumor-Infiltrating Lymphocytes Genetically Engineered with an Inducible Gene Encoding Interleukin-12 for the Immunotherapy of Metastatic Melanoma

Sadik H. Kassim, S. Rosenberg, R. Morgan, 2015, Clinical Cancer Research.

Cutting Edge: CD4+ T Cell Control of CD8+ T Cell Reactivity to a Model Tumor Antigen

N. Restifo, M. Dudley, D. Surman, 2000, The Journal of Immunology.

Augmented Lymphocyte Expansion from Solid Tumors With Engineered Cells for Costimulatory Enhancement

S. Rosenberg, M. Dudley, S. Feldman, 2011, Journal of immunotherapy.

Challenges and progress in lentiviral vector bioprocessing

Mark Dudley, Eugenio Macchiarulo, Phil Bassett, 2018, Cell and Gene Therapy Insights.

Transfer of a TCR gene derived from a patient with a marked antitumor response conveys highly active T-cell effector functions.

S. Rosenberg, R. Morgan, R. Hawley, 2005, Human gene therapy.

Thoracic metastasectomy for adoptive immunotherapy of melanoma: a single-institution experience.

S. Rosenberg, Leandro Mercedes, D. Schrump, 2010, The Journal of thoracic and cardiovascular surgery.

Single-pass, closed-system rapid expansion of lymphocyte cultures for adoptive cell therapy.

S. Rosenberg, M. Dudley, J. Wunderlich, 2009, Journal of immunological methods.

Liver Resection for Metastatic Melanoma with Postoperative Tumor-Infiltrating Lymphocyte Therapy

S. Steinberg, S. Libutti, S. Rosenberg, 2009, Annals of Surgical Oncology.

Adoptive Cell Transfer and Lymphodepleting Chemotherapy for the Treatment of Metastatic Melanoma

R. Morgan, K. Matsuda, M. Dudley, 2011 .

Selective Growth, In Vitro and In Vivo, of Individual T Cell Clones from Tumor-Infiltrating Lymphocytes Obtained from Patients with Melanoma

S. Rosenberg, P. Robbins, M. Dudley, 2004, The Journal of Immunology.

Functional Heterogeneity of Vaccine-Induced

Steven A. Rosenberg, Francesco M. Marincola, Mark E. Dudley, 2013 .

Proteasomal cleavage does not determine immunogenicity of gp100-derived peptides gp100209-217 and gp100209-217T210M

F. Marincola, C. Servis, M. Dudley, 2004, Cancer Immunology, Immunotherapy.

Lymphocytes Mononuclear Cells and Tumor-Infiltrating Reactivity to Nonreactive Peripheral Blood Confers Both High Avidity and Tumor Gene Transfer of Tumor-Reactive TCR

S. Rosenberg, D. Powell, R. Morgan, 2006 .

Cell Transfer Therapy for Cancer: Lessons from Sequential Treatments of a Patient With Metastatic Melanoma

Steven A. Rosenberg, Douglas J. Schwartzentruber, S. Rosenberg, 2003, Journal of immunotherapy.

A Simplified Method for the Clinical-scale Generation of Central Memory-like CD8+ T Cells After Transduction With Lentiviral Vectors Encoding Antitumor Antigen T-cell Receptors

Richard A. Morgan, Steven A. Rosenberg, S. Rosenberg, 2010, Journal of immunotherapy.

Tumor-specific CD4+ Melanoma Tumor-infiltrating Lymphocytes

S. Rosenberg, J. Yang, M. Dudley, 2012, Journal of immunotherapy.

To bead or not to bead.

M. Dudley, Mark E Dudley, 2003, Journal of immunotherapy.

Clinical Cancer esearch cer Therapy : Clinical cessful Treatment of Melanoma Brain R astases with Adoptive Cell Therapy

S. Rosenberg, J. Butman, J. Yang, 2010 .

astases with Adoptive Cell Therapy

S. Rosenberg, J. Butman, J. Yang, 2010 .

Clinical scale rapid expansion of lymphocytes for adoptive cell transfer therapy in the WAVE® bioreactor

S. Rosenberg, M. Dudley, M. Parkhurst, 2012, Journal of Translational Medicine.

Minimally invasive liver resection to obtain tumor-infiltrating lymphocytes for adoptive cell therapy in patients with metastatic melanoma

S. Rosenberg, Suzanne Inchauste, D. White, 2012, World Journal of Surgical Oncology.

Construction and Pre-Clinical Evaluation of An Anti-CD19 Chimeric Antigen Receptor

W. Wilson, S. Rosenberg, R. Morgan, 2008 .

High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy.

S. Rosenberg, H. Zeh, M. Dudley, 1999, Journal of immunology.

B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells.

S. Rosenberg, R. Morgan, J. Yang, 2012, Blood.

Levels of peripheral CD4(+)FoxP3(+) regulatory T cells are negatively associated with clinical response to adoptive immunotherapy of human cancer.

S. Steinberg, S. Rosenberg, D. Schrump, 2012, Blood.

PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors.

D. Douek, S. Rosenberg, S. Darko, 2014, The Journal of clinical investigation.

Augmented Lymphocyte Expansion from Solid Tumors With Engineered Cells for Costimulatory Enhancement

S. Rosenberg, M. Dudley, S. Feldman, 2011, Journal of immunotherapy.

Expansion and characterization of T cells transduced with a chimeric receptor against ovarian cancer.

S. Rosenberg, P. Hwu, M. Dudley, 2000, Human gene therapy.

Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.

S. Steinberg, S. Rosenberg, D. Citrin, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Tumor Infiltrating Lymphocyte Therapy for Metastatic Melanoma: Analysis of Tumors Resected for TIL

S. Steinberg, S. Rosenberg, D. White, 2010, Journal of immunotherapy.